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AASLD News: January 14, 2010

Hepatology Table of Contents 
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As an AASLD Member, you can also visit the Hepatology EarlyView, which gives members direct access to the journal articles ahead of print publication.

Comments from the Editors

Darwin, development, Drosophila, and disease

Editorials

Lipidomic dissection of nonalcoholic steatohepatitis: Moving beyond foie gras to fat traffic

Natural killer group 2 member D, its ligands, and liver disease: Good or bad?

Multifaceted perspective of the waiting list for liver transplantation: The value of pharmacokinetic models

Fluorescent in situ hybridization testing in primary sclerosing cholangitis: Useful testing or a random chance result?

Hepatocytes from induced pluripotent stem cells: A giant leap forward for hepatology

Viral Hepatitis

Liver stiffness identifies two different patterns of fibrosis progression in patients with hepatitis C virus recurrence after liver transplantation

Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells

Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles

Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope

Control of hepatitis B virus replication by innate response of HepaRG cells

Long-term efficacy of tenofovir monotherapy for hepatitis B virus-monoinfected patients after failure of nucleoside/nucleotide analogues

Interleukin-17-producing CD4+ T cells increase with severity of liver damage in patients with chronic hepatitis B

Steatohepatitis/Metabolic Liver Disease

Major histocompatibility complex class I-related chains A and B (MIC A/B): A novel role in nonalcoholic steatohepatitis

Increased tumor necrosis factor -converting enzyme activity induces insulin resistance and hepatosteatosis in mice

Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease

Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis

Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis

Hepatobiliary Malignancies

Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1

(ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive hepatocellular carcinoma

Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells

Use of sorafenib in patients with hepatocellular carcinoma before liver transplantation: A cost-benefit analysis while awaiting data on sorafenib safety

Autoimmune, Cholestatic and Biliary Disease

Long-term outcomes of positive fluorescence in situ hybridization tests in primary sclerosing cholangitis

Mouse organic solute transporter deficiency enhances renal excretion of bile acids and attenuates cholestasis

Liver Failure/Cirrhosis/Portal Hypertension

Liver injury in acute fatty liver of pregnancy: Possible link to placental mitochondrial dysfunction and oxidative stress

Increased caffeine consumption is associated with reduced hepatic fibrosis

Acute portal vein thrombosis unrelated to cirrhosis: A prospective multicenter follow-up study

Liver Failure, Cirrhosis and Portal Hypertension

Predictors of response to therapy with terlipressin and albumin in patients with cirrhosis and type 1 hepatorenal syndrome

Liver Injury/Regeneration

Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation

Liver Injury and Regeneration

Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice

Liver Injury/Regeneration

Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine

Liver Biology/Pathobiology

Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression

Steatohepatitis/Metabolic Liver Disease

Bone marrow transplantation demonstrates medullar origin of CD34+ fibrocytes and ameliorates hepatic fibrosis in Abcb4-/-mice

Liver Biology/Pathobiology

Mechanisms for increased expression of cholesterol 7-hydroxylase (Cyp7a1) in lactating rats

Folding defects in P-type ATP 8B1 associated with hereditary cholestasis are ameliorated by 4-phenylbutyrate

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

AASLD Practice Guidelines

The role of transjugular intrahepatic portosystemic shunt (TIPS) in the management of portal hypertension: Update 2009

Alcoholic liver disease

Rapid Communication

Generation of functional human hepatic endoderm from human induced pluripotent stem cells

Hepatology Elsewhere

IB kinase : A potential therapeutic target for obesity (and nonalcoholic fatty liver disease)?

N-acetylcysteine on its way to a broader application in patients with acute liver failure

Image of the Month

A case of fulminant hepatic failure in pregnancy

Correspondence

Hepatitis C virus infection, lipids, and coronary heart disease: A Pandora's box

Reply

New translational research on novel drugs for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells

Reply

Supporting evidence for natural killer T cell accumulation in progressive nonalcoholic fatty liver disease?

Reply

Minocycline sensitizes rodent and human liver mitochondria to the permeability transition: Implications for toxicity in liver transplantation

Minocycline protects against the mitochondria permeability transition after both warm and cold ischemia-reperfusion

Diagnostic criteria for autoimmune hepatitis: What is the gold standard?

Reply

An identification of the novel combination therapy for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells

Statins and hepatitis C virus: Friend or foe?

Human immunodeficiency virus and hepatitis C infections induce distinct immunologic imprints in peripheral mononuclear cells

Protection of mitochondrial genome integrity: A new stem cell property?

Limitations of the algorithm for the SAFE biopsy: A noninvasive fibrosis measure in chronic hepatitis C

Is it difficult to obtain an optimal liver biopsy specimen?

The cirrhosis risk score predicts liver fibrosis progression in patients with initially mild chronic hepatitis C

Correction

Corrections

Corrections