Add to Calendar 2019-09-20 07:00:00 2019-09-21 10:15:00 Emerging Topic Conference: The Genomics Revolution The conference will focus on genomics and the changing approach to diagnostics, management and research in adult and pediatric liver diseases. Arlington, VA 22202 United States AASLD alonzo.tolver@boldrstrategy.com America/Chicago public

Course Description / Needs Statement

The conference will focus on genomics and the changing approach to diagnostics, management and research in adult and pediatric liver diseases. This course will provide a broad overview of genomic technologies and how they may be applied to understand the genetic underpinnings of rare and complex liver disorders. Attendees will develop a better understanding of the true genomic contribution to liver disease, and how this data can lead to personalized approaches to medical therapy.

Program Chairs

  • Richard J. Thompson, MD, PhD
  • Kathleen M. Loomes, MD, FAASLD

Location

  • The Westin Crystal City
    1800 Jefferson Davis Hwy
    Arlington, VA 22202

Continuing Education

  • CME – 9.25 AMA PRA Category 1 Credits™
  • ABIM MOC – 9.25 points
  • ABP MOC – 9.00 points

Travel Note

US residents: Please review the Real ID Act regarding boarding federally regulated commercial aircrafts. Depending on your state of residence, you may need to provide a second form of identification at the airport.

Schedule Note

Breakfast is served at 7:00 am ET both days.

Registration Pricing

  • Member $325
  • Trainee & Assoc. Members $185
  • Student Member $90
  • Non-Member $540
    Any physician, scientist, or researcher with doctoral-level training who is not employed by Industry (pharma/device/etc.)
  • Trainee & Assoc. Non-Member $235
    Any physician, scientist or researcher in a training program as certified
    by the director of their training program. This category also includes, but is not limited to, the degrees of MS, NP, PA, RN, and other related or comparable degrees.
  • Student Non-Member $115
  • Industry $775
    Any Industry (pharma/device/etc.) employee with or without medical training.
  • Member $425
  • Trainee & Assoc. Members $210
  • Student Member $105
  • Non-Member $640
    Any physician, scientist, or researcher with doctoral-level training who is not employed by Industry (pharma/device/etc.)
  • Trainee & Assoc. Non-Member $260
    Any physician, scientist or researcher in a training program as certified
    by the director of their training program. This category also includes, but is not limited to, the degrees of MS, NP, PA, RN, and other related or comparable degrees.
  • Student Non-Member $130
  • Industry $875

Cancellation Policy

Requests for cancellations must be submitted in writing to meetings@aasld.org.

Cancellations received by August 20, 2019 will be eligible for a full refund.

Cancellations received between August 21 – September 3, 2019 will be subject to a $50.00 cancellation fee.

Cancellations received on or after September 4, 2019 are not eligible for a refund.

Any Industry (pharma/device/etc.) employee with or without medical training.

Session I: Big Projects
Moderator: Richard J. Thompson, MD, PhD

  • 8:00 am – 8:05 am
    Introduction
    TBD
  • 8:05 am – 8:25 am
    Personalizing Care Through Genomics
    Teri Manolio, MD, PhD
  • 8:25 am – 8:45 am
    Exome Sequencing in Gene Discovery and Diagnosis
    Nancy Spinner, PhD
  • 8:45 am – 9:05 am
    Creating Collaborative Databases
    Steven Harrison, PhD
  • 9:05 am – 9:25 am
    Pitfalls of Genetic Testing
    Lisa S. Parker, PhD
  • 9:25 am – 9:45 am
    Panel Discussion / Q&A
  • 9:45 am – 10:05 am
    Break

    Session II: Genetic Liver Diseases
    Moderator: Kathleen M. Loomes, MD, FAASLD

    • 10:05 am – 10:25 am
      Genetic Cholestasis in Children
      Laura Bull, PhD
    • 10:25 am – 10:45 am
      Genetic Cholestasis in Adults
      Catherine Williamson, PhD
    • 10:45 am – 11:05 am
      Genetic Determinants of Cholangiopathies
      Richard J. Thompson, MD, PhD
    • 11:05 am – 11:30 am
      Panel Discussion / Q&A
    • 11:30 am – 1:00 pm
      Lunch and Poster Session

    Session III: Genetics of Common Disease
    Moderator: Binita M. Kamath, MBBChir

    • 1:00 pm – 1:20 pm
      Genetics of Drug Induced Liver Injury
      Merrie Mosedale, PhD
    • 1:20 pm – 1:40 pm
      Genetics of NAFLD
      Quentin M. Anstee, MBBS, PhD, FRCP
    • 1:40 pm – 2:00 pm
      Genetic Etiology of Liver Cancer
      Silvia M. Vilarinho, MD, PhD
    • 2:00 pm – 2:30 pm
      Panel Discussion / Q&A

    Session IV: Genetic Contribution to Complex Disease
    Moderator: Nancy Spinner, PhD

    • 2:30 pm – 2:50 pm
      Genetic Susceptibility to Biliary Atresia
      Saul J. Karpen, MD, PhD, FAASLD
    • 2:50 pm – 3:10 pm
      Genetic Modifiers in Inherited Liver Disease
      Kathleen M. Loomes, MD, FAASLD
    • 3:10 pm – 3:30 pm
      Genetics of Autoimmune Liver Disease
      Gideon Hirschfield, FRCP, PhD
    • 3:30 pm – 3:50 pm
      Epigenetics and Disease Phenotypes
      TBD
    • 3:50 pm – 4:20 pm
      Panel Discussion / Q&A

    Session V: Beyond Sequence Variation
    Moderator: Kathleen M. Loomes, MD, FAASLD

    • 8:00 am – 8:20 am
      miRNA as a Biomarker of Acute Rejection in Liver Transplant
      Brendan James Keating, PhD
    • 8:20 am – 8:40 am
      The Role of microRNA’s in the Pathophysiology of Liver Disease
      Justin L. Mott, MD, PhD
    • 8:40 am – 9:00 am
      Precision Medicine in CF
      Joseph Zabner, MD
    • 9:00 am – 9:20 am
      Panel Discussion / Q&A
    • 9:20 am – 9:40 am
      Break

    Session VI: Targeted Interventions
    Moderator: Richard J. Thompson, MD, PhD

    • 9:40 am – 10:00 am
      Personalized Disease Models Using iPS Cell Derived Models
      Binita M. Kamath, MBBChir
    • 10:00 am – 10:20 am
      Novel Therapeutics in Liver Disease
      Gyongyi Szabo, MD, PhD, FAASLD
    • 10:20 am – 10:40 am
      Application of Genomic Data to Clinical Practice
      Stephen L. Guthery, MD
    • 10:40 am – 11:00 am
      Panel Discussion / Q&A
    • 11:00 am – 11:15 am
      Wrap-up
      Kathleen M. Loomes, MD, FAASLD and Richard J. Thompson, MD, PhD
    • 11:15 am
      Adjourn

    US Residents: Review the Real ID Act regarding boarding federally regulated commercial aircrafts. Depending on your state of residence, you may need to provide a second form of identification at the airport.

    Venue

    The Westin Crystal City
    1800 Jefferson Davis Hwy
    Arlington, VA 22202

    Make your Online Reservations
    Phone: 703-486-1111

    If you are calling to make a reservation, let the hotel representative know you are attending the AASLD meeting.

    Rates

    Single/Double $165 per night plus tax

    Cancellation Policy

    All hotel room reservations must be cancelled within 48 hours of scheduled arrival date to receive a refund.

    Airports

    • Ronald Reagan National Airport (DCA)
    • Washington Dulles International Airport (IAD)

    Ground Transportation

    Shuttle Services
    Complimentary shuttle services to the hotel are provided from 5:30 am – 11:00 pm daily to and from the DCA airport. There is no shuttle service from the IAD airport.

    Taxi
    From DCA the taxi fare estimation is $12 (one way) and from IAD is $65. Both are estimations for one-way fares.

    Metro / Subway / Public Transportation
    The nearest WMATA metro station is the Crystal City Metro Station (both Blue and Yellow lines). The metro station is .1 miles from the Westin Crystal City Hotel.

    Parking

    Self-parking at the hotel is $16 hourly and $34 daily. Valet parking fee is $40 daily.

    Needs Statement

    The conference will focus on genomics and the changing approach to diagnostics, management and research in adult and pediatric liver diseases. This course will provide a broad overview of genomic technologies and how they may be applied to understand the genetic underpinnings of rare and complex liver disorders. Attendees will develop a better understanding of the true genomic contribution to liver disease, and how this data can lead to personalized approaches to medical therapy.

    Learning Objectives

    Upon completion of this activity, learners will be able to:

    • Get a better understanding of how genomic data can be used to answer research questions
    • How to properly use genomic testing in the diagnosis and management of liver disease
    • Get insight into the existing datasets that can be used in research and clinical care.

    Target Audience

    • Hepatologists
    • Gastroenterologists
    • Surgeons
    • Fellows/Trainees

    This activity was planned in the context of the following ACGME/IOM/IPEC competencies:

    • Patient Care and Procedural Skills
    • Provide Patient-centered Care
    • Medical Knowledge
    • Work in Interdisciplinary Teams
    • Roles/Responsibilities
    • Employ Evidence-based Practice
    • Teams and Teamwork
    • Professionalism
    • Utilize Informatics

    Credits Offered

    • Continuing Medical Education (CME): 9.25 AMA PRA Category 1 Credits™
    • ABIM Maintenance of Certification (MOC): 9.25 Points
    • ABP Maintenance of Certification (MOC): 9.00 Points

    Accreditation and Designation Statements

    Continuing Medical Education (CME)

    The American Association for the Study of Liver Diseases (AASLD) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. AASLD designates this live activity for a maximum of 9.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    American Board of Internal Medicine Maintenance of Certification (MOC)

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 9.25 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC points.

    American Board of Pediatrics Maintenance of Certification (MOC)

    Successful completion of this CME activity, which includes participation in the activity, with individual assessments of the participant and feedback to the participant, enables the participant to earn 9.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABP MOC points.

    CME Credits

    Physicians and other health care professionals seeking 9.25 AMA PRA Category 1 Credits™ for this live continuing medical education activity must complete an evaluation by Monday, October 21. A link to the CME evaluation will be emailed to attendees after the conference.

    MOC Points

    Physicians seeking ABIM and/or ABP MOC points must complete the CME and MOC evaluation by Monday, October 21. Requests for MOC after this date will not be honored. The MOC evaluation is included in the CME evaluation.

    MOC Points will be reported to the ABIM and ABP by the end of October 2019 for attendees who successfully complete the MOC evaluation.

    Submission Deadlines

    • Open: Wednesday, May 29, 2019
    • Close: Tuesday, July 30, 2019

    Overview

    Abstracts submitted will be reviewed by the Program Chairs for potential poster presentation. If selected, the presenting author will be required to accept the invitation to present, register for the conference, and provide current financial disclosure information.

    Abstract notification will be sent to presenting authors by mid-August.

    Questions

    For questions about the abstract submission process, send an email to abstracts@aasld.org.

    Title

    The title should be brief, but long enough to identify the nature of the study. Omit author names and medical degrees and institutional appointments in the title. The maximum for the title character count is 300.

    Abstract Body

    The body of the abstract needs to include:

    • A background
    • Description of methods
    • Summary of results obtained
    • Statement of conclusion reached

    There is a set 3,000 maximum character count for the abstract body.

    Attachments

    You may include any supporting images/tables. Images and tables are not a part of the overall character count.
    Accepted files: pdf, jpg, jpeg, png, csv, doc(x), and ppt under 5MB

    Author Types

    Only one presenting and corresponding author may be selected – see author definitions below

    • Co-Author – One of several authors who provided a significant contribution to the abstract.
    • Corresponding Author – This author will receive all notifications regarding the abstract, and will be expected to make any changes requested by the abstract reviewers.
    • Presenting Author – The author who will be presenting the poster at the meeting.

    The maximum number of authors on an abstract is 30.

    Questions

    For questions about the abstract submission process, send an email to abstracts@aasld.org.

    Ethics Policy

    The initial responsibility for adherence to ethical guidelines lies with the responsible investigators submitting their research findings to AASLD meetings or journals. First, for reports of research using human subjects, provide assurance that (a) informed consent in writing was obtained from each patient and (b) the study protocol conformed to the ethical guidelines of the 1975 Declaration of Helsinki as reflected in a prior approval by the appropriate institutional review committee. Refer to individual patients by number, not by initials. HEPATOLOGY will only accept papers for review from liver transplant centers that explicitly state that no donor organs were obtained from executed prisoners or other institutionalized persons. Papers without such explicit statements will be returned without review.

    Second, in studies involving animal experimentation, provide assurance that all animals received humane care according to the criteria outlined in the Guide for the Care and Use of Laboratory Animals [PDF] prepared by the National Academy of Sciences and published by the National Institutes of Health (NIH publication 86-23 revised 1985).

    Disclosure Policy

    It is the policy of the American Association for the Study of Liver Diseases (AASLD) to ensure balance, independence, objectivity, and scientific rigor in all its individually or jointly provided educational programs. All faculty/authors participating in any AASLD sponsored programs, as well as planners and committee members, are expected to disclose any real or apparent conflict(s) of interest that may have a direct bearing on the subject matter of the continuing medical education program.

    All abstract authors must complete their own financial disclosure statement either disclosing all financial relationships with commercial interests or indicating that none exist. Submitting authors will NOT be allowed to submit disclosures on a co-author's behalf.

    A limited number of travel awards will be available for trainees in the field of hepatology with a special interest in the conference topic. In order to qualify for a travel award, an abstract on related research must be submitted and accepted.

    Press Policies and Guidelines

    The American Association for the Study of Liver Diseases provides credentialed media with complimentary press registration. Below is information on eligibility and the credentialing process.

    Press Eligibility

    Journalists, and contributing freelancers, employed by a recognized news organization are eligible to apply for press registration. To be eligible for press registration, media in all categories must be directly involved in the creation of news content for organizations that meet these criteria:

    • Publish original editorial news coverage in a regular news section
    • Have complete editorial freedom from advertisers, funders and/or sponsors
    • If sponsored, the outlet has multiple sponsors (no single-sponsored publications)
    • Advertisers, sponsors, paid editorial and other funding sources are clearly identified

    Bloggers

    Bloggers will receive press credentials on a case-by-case basis. Please include a link to recent liver disease, hepatology or health care science coverage with your registration for credentials. Finally, all blogs must demonstrate the dissemination of original, editorial news coverage and editorial freedom from advertisers and/or sponsors (single-sponsored blogs will not receive credentials; blogs with advertising must have multiple advertisers clearly identified).

    Photographers/Videographers

    Photographers, videographers, and/or other members of the multimedia team accompanying credentialed news outlets may register as media and provide a link to recent coverage from their team. Further credentialing may be required during the approval process.

    NOTE: AASLD has the right to inspect the credentials of anyone registering as media and reserves the right to deny media registration to anyone who does not meet the above guidelines. AASLD also has the right to limit the number of media registrants from any one media outlet to ensure ample space for all media.

    Ineligible Registrants

    The following individuals are not eligible for press registration or access to the Newsroom:

    • Individuals who receive exhibitor passes
    • Publishers or a publications’ advertising, marketing, public relations, sales, circulation, or any other non-editorial function representatives
    • Industry/exhibitor press officers and their public relations consultants
    • Financial or business analysts
    • Educational program developers (including CME writers and editors)
    • Trade media management personnel
    • Editors, writers, and scientific advisory board members for journals that do not have editorial news sections
    • Companies or organizations producing publications, videos, and/or other electronic media intended for internal use, marketing, advertising, financial analysis, or public relations purposes
    • Media who produce a communications vehicle that is sponsored by a single organization or whose revenue for the publication or issue of a publication depends solely on coverage of 2019 AASLD Emerging Topic Conference, The Genomics Revolution: Changing Our Approach to Diagnostics, Management and Research in Adult and Pediatric Liver Disease
    • Media who produce a communications vehicle that uses the AASLD’s name or logo, or the Emerging Topic Conference name/logo to imply endorsement from AASLD

    NOTE: AASLD prohibits the development of CME content based on information presented at its meetings. CME writers and editors, and those writers and editors working on behalf of organizations that have written CME based on AASLD meetings, are not eligible for press passes.

    Prohibited Activities

    • Sales, marketing or representing a company for the purposes of obtaining advertising, subscriptions, selling photography/video production, or other products or services from any registrant or exhibitor
    • Misrepresentation of role or activities to obtain media registration
    • Developing or assisting in the development of continuing medical education programs
    • Soliciting presenters and/or attendees for inclusion in CME programs
    • Publishing or posting presentation slides, live streams of meeting presentations, or sharing copyrighted meeting materials without written permission.

    Video/Audio Recording

    Television and video crews are required to check in immediately with AASLD staff each day.

    Television and video crews must be wearing press badges. Shooting schedules must be provided to AASLD staff in advance of the meeting.

    Permission of the speaker and moderator must be obtained by the journalist before recording or photographing presentations. Artificial light and flash photography cannot be used during presentations. Handheld audio recorders and still cameras are acceptable, assuming that intellectual property copyrights are respected.

    Under no circumstances may presentations be rebroadcasted.

    Any images from the meeting should be credited to: 2019 AASLD Emerging Topic Conference, The Genomics Revolution: Changing Our Approach to Diagnostics, Management and Research in Adult and Pediatric Liver Disease.

    Use of Insignias and Logos

    Insignias and logos of the AASLD, this meeting or AASLD Foundation are proprietary marks. Use of these in any fashion, by any entity, for any purpose, is prohibited without the written permission of AASLD. The use of insignias, logos and images that mislead the intended audience to believe that a piece or production is coming from the AASLD is strictly prohibited and will result in the denial of press credentials for future meetings.

    Dedicated Websites and Newsletters

    If you intend to present coverage of this meeting in a dedicated website or newsletter, please include the following disclaimer at the top of your piece: This information is brought to you by [insert organization name] and is not sponsored by, nor a part of, the Association for the Study of Liver Diseases or 2019 AASLD Emerging Topic Conference, The Genomics Revolution: Changing Our Approach to Diagnostics, Management and Research in Adult and Pediatric Liver Disease. Additionally, you may not use the AASLD’s logo or name to imply affiliation.

    AASLD reserves the right to request promotional activities violating this policy be edited or removed. Failure to comply with these guidelines may result in loss of press credentials for future meetings.

    Applying for Press Credentials

    Requests for press credentials should be sent to media@aasld.org and must be sent by Friday, September 13, 2019. Onsite press registration cannot be accommodated. When sending your request for credentials, include two of the following:

    • Bylined news coverage
    • Copy of official press credentials
    • Assignment letter
    • Two recent posts about liver disease and/or health care (for bloggers)