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Current Trends in Liver Regeneration and Repair

Date/Time

  • Saturday, November 9, 8:00 am - 5:00 pm

Program Chairs

  • George K. Michalopoulos, PhD, FAASLD
  • Xiao-Ming Yin, MD, PhD, FAASLD

Session Description / Needs Statement

The liver is constantly exposed to external and internal damaging factors, yet it can regenerate and repair itself. With the help of novel tools, we now know more about the mechanisms of this process. At this symposium, experts report new research on liver regeneration and repair and how this knowledge may facilitate clinical applications to rescue and restore liver function.

Learning Objectives

Upon completion of this activity, participants will be able to:

  • Recognize the impact of liver regeneration and repair in the development of hepatic diseases
  • Discuss critical roles of liver regeneration and repair in liver physiology
  • Discuss the new knowledge and new tools available to study liver regeneration and repair
  • Identify new therapeutic approaches to rescue and restore live functions

Continuing Education

  • CME – 7.00 AMA PRA Category 1 Credits™

To view full programming being offered at The Liver Meeting®, visit the 2019 Online Program. [Coming Summer 2019]

Session I: Liver Regeneration

Moderators: TBD

  • 8:00 am – 8:05 am
    Welcome and Introductions
  • 8:05 am – 8:35 am
    Receptor Tyrosine Kinase Pathways in Normal and Regenerating Liver
    TBD
  • 8:35 am – 9:00 am
    Hepatic Macrophages in Liver Regeneration
    TBD
  • 9:00 am – 9:25 am
    Stellate Cells in Normal and Regenerative Liver Biology
    TBD
  • 9:25 am – 9:50 am
    Developmental Pathways in Liver Regeneration
    TBD
  • 9:50 am – 10:00 am
    Q & A / Panel Discussion
  • 10:00 am –10:15 am
    Break

Session II: Hepatocyte-biliary Cell Transdifferentiation

Moderators: TBD

  • 10:15 am – 10:40 am
    Cholangiocyte Proliferation in Liver Regeneration
    TBD
  • 10:40 am – 11:05 am
    Cholangiocyte Development and Repair
    TBD
  • 11:05 am – 11:30 am
    Regeneration and Facultative Stem Cell Functions in Cholangiocytes
    TBD
  • 11:30 am – 11:45 am
    Q&A / Panel Discussion
  • 11:45 am – 1:15 pm
    Intermission (includes travel time to Meet-the-Professor Luncheons)

Session III: Hepatic Progenitor Cells and Liver Repair

Moderators: TBD

  • 1:15 pm – 1:40 pm
    Role of Hepatic Progenitor Cells in Liver Injury
    TBD
  • 1:40 pm – 2:05 pm
    Senescence, Ductular Reaction and Hepatic Progenitor Expansion
    TBD
  • 2:05 pm – 2:30 pm
    Autophagy Regulates the Expansion of Hepatic Progenitor Cells in Liver Injury
    TBD
  • 2:30 pm – 2:55 pm
    Hepatic Progenitor Cells in Liver Regeneration and Reprogramming
    TBD
  • 2:55 pm – 3:10 pm
    Q&A / Panel Discussion
  • 3:10 pm – 3:30 pm
    Break

Session IV: Hepatic Reconstitution with iPSC And Liver Stem Cell Culture

Moderators: TBD

  • 3:30 pm – 3:55 pm
    Stem Cells, Organoid Culture for Liver Regeneration
    TBD
  • 3:55 pm – 4:20 pm
    Methodologies and Applications Related to iPSC Hepatocytes in Normal and Decellularized Livers
    TBD
  • 4:20 pm – 4:45 pm
    iPSC Hepatocytes: Successes and Hopes for Therapies
    TBD
  • 4:45 pm – 4:55 pm
    Q&A / Panel Discussion
  • 4:55 pm – 5:00 pm
    Closing Remarks