Register for the OnDemand Emerging Topic Conference: Multi-Omics Approaches for Cholestatic Liver Diseases!

Learn how multi-omics approaches can be a tool to understand, diagnose and to develop future treatments for cholestatic liver diseases. Register today for the 2023 OnDemand Emerging Topic Conference: Multi-Omics Approaches for Cholestatic Liver Diseases: From Diagnosis to Disease Mechanisms and Precision Medicine happening June 1-2 online.

During this two-day event, attendees will view OnDemand presentations and network directly with experts in a virtual environment.


June 1: Day one is an immersive experience in education around multi-omics that will address the contribution of multi-omics approaches to new liver biology knowledge and care of patients with a variety of chronic liver diseases.

Learn about advances to improve the understanding, diagnosis and treatment of liver diseases, including:

- Recent advances in “omics” technologies (i.e., genomic, proteomics, metabolomics) as applied to cholangiopathies and cholestatic liver diseases. 

- The crucial role of the microbiome and the environment in biliary diseases.

- Innovations in computational tools for large scale data integration.

- The use of human stem cell-based cell models (i.e., induced pluripotent stem cells (iPSCs) and 3D-organoids) as a complementary tool for precision medicine.

June 2: On day two, attendees have a chance to join deeper discussions around the topics covered during day one. Attendees will network in virtual Zoom rooms, with speakers, our program chairs and other attendees.

When & Where

Date: Thursday, June 1, 8:00 am - Friday, June 2, 10:00 am (EDT)
Location: Online

Program Chairs

    Learning Objectives

    1. To provide an overview of the current advances in multi-omics technologies and their contribution to the understanding, diagnosis and treatment of cholestatic liver diseases.
    2. To recognize the importance of stem-cell based human disease models and of organoids as a tool for functional validation of multi-omics data and to advance personalized medicine approaches for rare liver diseases.
    3. To identify current knowledge gaps and limitations for the introduction of these technologies in clinical practice.

    Target Audience

    • Hepatologists
    • Fellows/ Trainees
    • Gastroenterologists
    • Surgeons
    • Pharmacists

    Continuing Education

    The American Association for the Study of Liver Diseases (AASLD) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AASLD designates this live activity for a maximum of 8.75 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Agenda - June 1, 2023

    15 mins     Welcome and Course Objectives
                      Romina Fiorotto, PhD
    45 mins     Biliary Diseases: What Are the Missing Pieces?
                      Mario Strazzabosco, MD, PhD, FAASLD

    Session I: Genomics

    20 mins      Cholestatic Liver Diseases: Harnessing the Genetics and Epigenetics 
                       Gideon Hirschfield, FRCP, PhD
    20 mins      Next Generation Sequencing for Diagnosis of Infantile Cholestatic Diseases 
                       Richard Thompson, MD, PhD, FAASLD
    20 mins      The Transcriptomic of Biliary Atresia 
                       Alexander Miethke, MD
    20 mins      Liver Disease Immunophenotyping: When a Single Cell Matter
                       Sonya MacParland, PhD

    Session II: Proteomics and Metabolomics   

    20 mins      Ig Glycosylation in Autoimmune Cholangitis 
                       Xing Zhou, MD
    20 mins      Multispectral Imaging for In-situ Analysis of Hepatic Immune Cells in Chronic Liver Diseases 
                       Heather L. Stevenson-Lerner, MD, PhD
    20 mins      Serum Proteome for the Discovery of Biomarkers 
                       Pedro Rodrigues, PhD
    20 mins      FDA Perspective on Analytic Platforms for Biomarkers
                      Robert Schuck, PharmD, PhD

    Session III: Microbiome

    20 mins      Considerations when Designing a Human Microbiome Study
                       Debbie Shawcross, PhD, MBBS, MRCP
    20 mins      Bile Microbiome and Autoimmune Liver Diseases 
                       Christoph Schramm, MD
    20 mins      Microbiome-immune System Cross-talk in Cholestatic Diseases 
                       Naiara Beraza, MD
    20 mins      Microbiome-based Therapeutics
                       Jasmohan Bajaj, MD 


    Session IV: The Synergism Between Big Data and Disease Modeling

    20 mins      Stem Cell-based in Vitro Systems to Model Liver Diseases and Multi-omic Analysis 
                       Romina Fiorotto, PhD
    20 mins      How Can Large Databases Address the Challenges of Rare Diseases?
                      Binita M. Kamath, MBBChir
    20 mins      Personalized Medicine from Clinical Biospecimens
                       David N. Assis, MD

    Session V: Multi Omics Integration

    20 mins      A Multiomic Approach to Biological and Environmental  Pertubations 
                       Erin S. Baker, PhD
    20 mins      Studying Exposome in PSC 
                       Konstantinos N. Lazaridis, MD, FAASLD
    20 mins      Applying Artificial Intelligence (AI) in Cholestatic Liver Diseases 
                       Dennis Shung, MD
    20 mins      Bench to Bedside: How Can Omics be Translated into Clinic
                       Tom H. Karlsen, MD, PhD

    10 mins      Closing Remarks
                       Nidhi Jalan-Sakrikar, PhD

    Agenda - June 2, 2023

    10:00 - 10:30 AM

    Session 1 Genomics Roundtable

    Moderated by: Nanda Kerkar, MD, FAASLD

    10:30 - 11:00 AM

    Session 2 Proteomics and Metabolomics Roundtable

    Moderated by: Nisanne S. Ghonem, PhD

    11:00 – 11: 30 AM

    Session 3 Microbiome Roundtable

    Moderated by: Romina Fiorotto, PhD

    11:30 AM – 12:00 PM

    Session 4 The Synergism Between Big Data and Disease Modeling Roundtable

    Moderated by: Nidhi Jalan-Sakrikar, PhD 

    12:00 – 12:30 PM

    Session 5 Multi Omics Integration Roundtable

    Moderated by: Christopher L. Bowlus

    Registration Rates

    General, Trainee, Associate and Student

    General: Any physician, scientist, or researcher with doctoral-level training who is not employed by Industry (pharma/device/etc.)

    Trainee & Associate: Any physician, scientist or researcher in a training program as certified by the director of their training program. This category also includes, but is not limited to, the degrees of MS, NP, PA, RN, and other related or comparable degrees.

    Industry: Any Industry (pharma/device/etc.) employee with or without medical training.

    On or before May 21, 2023 Member Non-Member
    General $340 $570
    Trainee & Associate $195 $245
    Student $95 $120


    Any Industry (pharma/device/etc.) employee with or without medical training.

    On or before May 21, 2023 $775

    Registration Cancellation Policy

    Requests for cancellation must be submitted in writing to

    Cancellations received:

    • through May 21, 2023 at 11:59PM are subject to a 25% cancellation fee.

    • from May 22, 2023 and after are non-refundable.