
Register Today for the 2023 Emerging Topic Conference: NASH Cirrhosis: From Mechanisms to Management
Together, we can tackle NASH Cirrhosis. Don’t miss the 2023 Emerging Topic Conference: NASH Cirrhosis: From Mechanisms to Management, a joint event between the Fibrosis SIG and NAFLD SIG to discuss the most recent research in NASH cirrhosis in a bench-to-bedside approach.
Attendees can network with others interested in NASH cirrhosis and will get expert updates on:
-New mechanisms in reversing fibrosis in patients with NASH.
-New therapeutic agents to treat NASH cirrhosis.
-New clinical trials and regulatory science in the field of NASH cirrhosis.
You can register for this event alone or for the combo of the North American Viral Hepatitis Elimination Summit and NASH Cirrhosis Emerging Topic Conference.
When & Where
Date: Saturday, March 25, 10:00 am - Sunday, March 26, 4:30 pm (EDT) Location: JW Marriott Los Angeles L.A. Live | 900 West Olympic Boulevard | Los Angeles, CA 90015
Program Chairs

Learning Objectives
- Learn about new mechanisms in reversing fibrosis in patients with NASH
- Learn about new therapeutic agents to treat NASH cirrhosis
- Learn about new clinical trials and regulatory science in the field of NASH cirrhosis
Target Audience:
- Hepatologists
- Gastroenterologists
- Nurse Practitioners
- Pharmacists
- Surgeons
- Fellows/Trainees
Continuing Education
Continuing Medical Education (CME): 9.50 AMA PRA Category 1 Credits™
ABIM MOC points: 9.50 MOC points
Travel Note
US residents: Please review the Real ID Act regarding boarding federally regulated commercial aircrafts. Due to circumstances resulting from the COVID-19 pandemic, the Department of Homeland Security has extended the REAL ID enforcement deadline to May 7, 2025. Depending on your state of residence, you may need to provide a second form of identification at the airport.
Schedule Note
Please note, all times in the agenda are listed in Pacific Daylight Time (PDT) as this is an in-person only event in Los Angeles, CA.
Tentative Agenda - March 25, 2023
Session I
Session I: Epidemiology, Genetics and Epigenetics
Moderators: Robert F. Schwabe, MD and Mazen Noureddin, MD
8:00 - 8:05 am Welcome and Opening Remarks
8:05 - 8:30 am Epidemiology and Disease Burden of NASH Cirrhosis
Zobair M. Younossi, MD, MPH, FAASLD
8:30 - 8:55 am Ethnic and Gender Differences of NASH Cirrhosis
Lisa Van Wagner, MD
8:55 - 9:20 am State of Art-Lecture: Role of Genetics and Epigenetics in NASH Cirrhosis
Anna Mae Diehl, MD, FAASLD
9:20 - 9:40 am Q&A
9:40 - 10:20 am Break
Session II
Session II: Biomarkers: Bench to Bedside
Moderators: Ekihiro Seki, MD, PhD, FAASLD and Alina Allen, MD
10:20 - 10:45 am NAFLD Fibrosis Mechanism and Biomarkers: What’s on the Horizon in Pre-clinical Models?
Ekihiro Seki, MD, PhD, FAASLD
10:45 - 11:10 am Non-coding RNA and EVs in NASH Cirrhosis
Harmeet Malhi, MBBS, FAASLD
11:10 - 11:35 am The Microbiome: Therapeutic Target, Marker or Both?
Rohit Loomba, MD
11:35 - 11:55 am Q&A
11:55 am - 1:00 pm Break
Session III
Session III: Study Design: Pre-Clinical and Clinical
Moderators: Stephen A. Harrison, MD, FAASLD and Mary Rinella, MD, FAASLD
1:00 – 1:25 pm Therapeutic Targets in NASH: Discovery in Mice or Men?
Scott L. Friedman, MD, FAASLD
1:25 – 1:50 pm Human Studies Proof of Concept Design and Related Biomarkers
Laurent Castera, MD
1:50 – 2:15 pm Designing Clinical Trial in NASH Cirrhosis
Stephen A. Harrison, MD, FAASLD
2:15 – 2:40 pm Clinical Trial in NASH Cirrhosis: The Regulator Perspective
George Makar, MD, MSCR
2:40 – 3:05 pm Debate: The Decompensated NASH Cirrhotic: Too Late to Treat?
Meena Bansal, MD, FAASLD
3:05 – 3:30 pm Debate: Hepatic Safety in NASH Cirrhosis Clinical Trials
Naga P. Chalasani MD, FAASLD
3:30 – 3:50 pm Q & A
5:00 - 6:30 pm Networking Reception
Tentative Agenda - March 26, 2023
Session IV
Session IV: Mechanisms and Cellular Targets
Moderators: Anna Mae Diehl, MD, FAASLD and David A. Brenner, MD
8:00 - 8:05 am Opening Remarks
8:05 - 8:30 am Single Cell-based Analysis of Cellular Crosstalk in Human NASH and Fibrosis
Sonya MacParland, PhD
8:30 - 8:55 am Targeting Hepatic Stellate in NASH
Robert F. Schwabe, MD
8:55 - 9:20 am Targeting Hepatocyte Metabolism
Dongyin Guan, PhD
9:20 - 9:45 am Understanding and Targeting Macrophages in NASH
Neil Henderson, MD, MBChB, PhD
9:45 - 10:05 am Q & A
10:05 - 10:25 Break
Session V
Session V: Therapeutic Targets
Moderators: Meena Bansal MD, FAASLD and Naga P. Chalasani, MD, FAASLD
10:25 - 10:45 am Targeted Pathways in NASH Cirrhosis
Silvia Sookoian, MD, PhD
10:45 - 11:00 am Debate: GLP-1 in NASH Cirrhosis
Jörn M. Schattenberg, MD
11:00 - 11:15 am Debate: FGFs in NASH Cirrhosis
Mazen Noureddin, MD
11:15 - 11:30 am Debate: Drugs Targeting DNL in NASH Cirrhosis
Kathleen Corey, MD
11:30 - 11:45 am Debate: PPAR in NASH Cirrhosis
Manal F. Abdelmalek, MD, MPH, FAASLD
11:45 - 12:45 pm Lunch
12:45 - 1:00 pm Debate: Thyroid Hormone Receptors in NASH Cirrhosis
Naim Alkhouri, MD
1:00 - 1:15 pm Debate: FXRs in NASH Cirrhosis
Arun J. Sanyal, MD, FAASLD
1:15 - 1:30 pm Other Agents and Combination Therapies
Mary Rinella, MD, FAASLD
1:30 - 1:50 pm Q & A
Session VI
Session VI: NASH and Cirrhosis Consortia
Moderator: Neil C. Henderson, MD, MBChB, PhD, FAASLD and Ekihiro Seki, M, PhD, FAASLD
1:50 - 2:05 pm An Update from the NASH CRN
Brent Tetri, MD, FAASLD
2:05 - 2:20 pm The NIDDK Liver Cirrhosis Network and Statin Trial
Norah Terrault, MD, FAASLD
2:20 - 2:40 pm Q & A
2:40 pm Conference Adjourned
Anna Mae Diehl, MD, FAASLD
Registration Rates: NASH Cirrhosis: From Mechanisms to Management
General
Any physician, scientist, or researcher with doctoral-level training who is not employed by Industry (pharma/device/etc.)
Member | Non-Member | |
---|---|---|
On or After February 24, 2023 | $450 | $670 |
Trainee & Associate
Any physician, scientist or researcher in a training program as certified by the director of their training program. This category also includes, but is not limited to, the degrees of MS, NP, PA, RN, and other related or comparable degrees.
Member | Non-Member | |
---|---|---|
On or After February 24, 2023 | $220 | $275 |
Student
Member | Non-Member | |
---|---|---|
On or After February 24, 2023 | $110 | $135 |
Industry
Any Industry (pharma/device/etc.) employee with or without medical training.
Industry | ||
---|---|---|
On or After February 24, 2023 | $920 |
Patients, Patient Advocates and Caregivers
Patients, Patient Advocates and Caregivers | ||
---|---|---|
Rate | Complimentary |
Registration Combo-Pricing for the North American Viral Hepatitis & NASH Cirrhosis Emerging Topic Conference
General
Any physician, scientist, or researcher with doctoral-level training who is not employed by Industry (pharma/device/etc.)
Member | Non-Member | |
---|---|---|
On or After February 24, 2023 | $630 | $940 |
Trainee & Associate
Any physician, scientist or researcher in a training program as certified by the director of their training program. This category also includes, but is not limited to, the degrees of MS, NP, PA, RN, and other related or comparable degrees.
Member | Non-Member | |
---|---|---|
On or After February 24, 2023 | $310 | $390 |
Student
Member | Non-Member | |
---|---|---|
On or After February 24, 2023 | $150 | $190 |
Industry
Any Industry (pharma/device/etc.) employee with or without medical training.
Industry | ||
---|---|---|
On or After February 24, 2023 | $1,290 |
Patients, Patient Advocates and Caregivers
Patients, Patient Advocates and Caregivers | ||
---|---|---|
Rate | Complimentary |
Registration Cancellation Policy
Requests for cancellations must be submitted in writing to meetings@aasld.org.
Cancellations received by Thursday, February 23, 2023 will be refunded in full.
Cancellations received between February 24 – March 6, 2023 will be subject to a $50.00 cancellation fee.
Cancellations received on or after March 7, 2023 are not eligible for a refund.
Housing
Venue
JW Marriott Los Angeles L.A. Live
900 W Olympic Blvd
Los Angeles, CA, 90015
Phone: 213-765-8600
*When calling to make a reservation, please let the hotel representative know that you are attending the AASLD NASH Cirrhosis Conference.
Rates
Single/Double $259 per night plus tax
Discounted rates are available until March 3, 2023.
Cancellation Policy
Cancel your reservation for no charge until 72 hours prior to your arrival date.
Please note that the hotel will assess a fee of (1) night of your room charge (for the first night of your reservation) USD if you must cancel after this deadline.
Parking
Valet Daily: $53.90
Electric Car Charging Station Available
Airports
Los Angeles International Airport (LAX) - 17.2 miles from hotel
Hollywood Burbank Airport (BUR) - 16 miles from hotel