Cases of Confounding Cholestasis: Navigating the Diagnostic and Therapeutic Challenges of PFICs

Nov 05 2026
Convention Center: Four Seasons Ballroom 4
12:00 PM - 1:30 PM
CE Credits CE Credits

Description

Progressive familial intrahepatic cholestasis (PFIC) and Alagille syndrome (ALGS) are rare, heritable cholestatic liver diseases. Typically recognized in pediatric settings, they can present across the lifespan and pose particular challenges in adults. This interactive, case-based symposium will improve clinicians' competence in recognizing, diagnosing, and managing PFIC and ALGS in adults.

  • Physicians: maximum of 1.50 AMA PRA Category 1 Credits™
  • Pharmacists: 1.50 contact hours (0.15 CEUs)
  • Nurse Practitioners/Nurses: 1.50 Nursing contact hours
  • Supported by: Ipsen Biopharmaceuticals, Inc.
  • Organized by: Clinical Care Options, LLC dba Decera Clinical Education in partnership with Progressive Familial Intrahepatic Cholestasis (PFIC) Network
  • For more information and to register, visit: https://deceraclinical.com/CholestasisDenver26

Objectives

  • Assess for late-onset and adult-presenting genetic cholestatic disorders in patients with suspected mimics or established diagnoses that warrant reevaluation
  • Apply an evidence-informed diagnostic framework that incorporates systematic use of genetic testing to evaluate subtype-specific presentations in patients with suspected PFIC or ALGS across the lifespan
  • Devise individualized, evidence-informed treatment and symptom management strategies for adults with PFIC and Alagille syndrome
  • Implement a multidisciplinary care plan that integrates long-term disease monitoring, transition of care planning, and family-centered genetic counseling for patients with PFIC and Alagille syndrome