Eleonora Scorletti, MD, PhD

Eleonora Scorletti, MD, PhD, is an Assistant Professor in the Department of Medicine, Division of Gastroenterology and Hepatology, and Director of Translational Metabolic Liver Research at the Johns Hopkins University School of Medicine. She is a physician-scientist whose research focuses on understanding the genetic and metabolic mechanisms underlying metabolic dysfunction-associated steatotic liver disease (MASLD) and its relationship with cardiometabolic health and biological aging.Her research integrates human genetics, recall-by-genotype deep phenotyping, and induced pluripotent stem cell-derived models to investigate lipid metabolism, lipid droplet biology, and the molecular pathways linking liver disease, metabolic dysfunction, and aging. Her work aims to uncover mechanisms driving disease susceptibility and progression and to identify novel targets for prevention and treatment.