Advances in Primary Biliary Cholangitis: Real-World Therapeutics, Biomarkers, and Patient-Centered Outcomes

Description

This session reviews real-world and trial data on PBC therapeutics — including elafibranor, seladelpar, and linerixibat — alongside emerging biomarkers and digital tools for tracking pruritus and disease activity.

Presentations

5:00 PM - 5:15 PM
Convention Center - Bluebird Ballroom 1B
Recorded session

Elafibranor Versus Seladelpar in UDCA-Treated Primary Biliary Cholangitis: A 111-Health-System Propensity-Matched Comparative Effectiveness Study

Mohammad Alabbas, M.D | Abstract Presenter
5:15 PM - 5:30 PM
Convention Center - Bluebird Ballroom 1B
Recorded session

Real-World Efficacy of Elafibranor in patients with Primary Biliary Cholangitis: Experience from a community-based hepatology practice

Rida Nadeem, MD | Abstract Presenter
5:30 PM - 5:45 PM
Convention Center - Bluebird Ballroom 1B
Recorded session

Serum IgM as a Prognostic Biomarker Linked to Intrahepatic Immune Activation in Primary Biliary Cholangitis: Insights from Histopathology and Single-cell Analysis 

Taiki Okumura, MD | Abstract Presenter
5:45 PM - 6:00 PM
Convention Center - Bluebird Ballroom 1B
Recorded session

Improved modulation of pruritic and pharmacodynamic biomarkers with linerixibat added to a stable background of bile acid binding resins or peroxisome proliferator-activated receptor agonists in GLISTEN

Andreas E. Kremer, MD, PhD | Abstract Presenter
6:00 PM - 6:15 PM
Convention Center - Bluebird Ballroom 1B
Recorded session

First-in-disease objective assessment of scratch and sleep patterns using a wearable digital health tool in primary biliary cholangitis: The LUMINARIA study 

Cynthia Levy, MD, FAASLD | Abstract Presenter

Objectives

  • Evaluate emerging therapeutic strategies for PBC by comparing real-world and clinical trial evidence for therapies
  • Assess the role of novel biomarkers and translational science in PBC
  • Incorporate patient-centered and digital health outcome measures into PBC management