Industry Research Showcase

Description

This session features industry-sponsored preclinical and translational research spanning novel therapeutics for Alagille syndrome, PSC, alcohol use disorder, and decompensated cirrhosis, plus hepatocyte engineering advances.

Presentations

8:00 AM - 8:15 AM
Convention Center - Bluebird Ballroom 1B
Recorded session

ART4, a Translation-Enhancing Antisense Oligonucleotide, Restores JAG1 Expression and Improves Liver Disease in Preclinical Models of Alagille Syndrome 

Xuehai Liang, Ph.D | Abstract Presenter
8:15 AM - 8:30 AM
Convention Center - Bluebird Ballroom 1B
Recorded session

Pemvidutide Treatment Reduces Alcohol Intake in a Lean Golden Syrian Hamster Model

John J Suschak, PhD | Abstract Presenter
8:30 AM - 8:45 AM
Convention Center - Bluebird Ballroom 1B
Recorded session

Suitability of intravenous administration of Regenerative Macrophage Therapy for the treatment of decompensated cirrhosis

Lara Campana | Abstract Presenter
8:45 AM - 9:00 AM
Convention Center - Bluebird Ballroom 1B
Recorded session

Targeting bile composition in PSC: RTY-406, a dual-acting ABCB4/BSEP Positive Functional Modulator reduces disease-relevant markers in a mouse model and non-human primate

Eric Bell, PhD | Abstract Presenter
9:00 AM - 9:15 AM
Convention Center - Bluebird Ballroom 1B
Recorded session

Circulating protein biomarkers associated with reductions in liver fat and visceral and subcutaneous adiposity in adults with obesity and MASLD with retatrutide treatment

YoSon Park, PhD | Abstract Presenter
9:15 AM - 9:30 AM
Convention Center - Bluebird Ballroom 1B
Recorded session

Closing the maturation gap: machine learning-driven optimization of hPSC-derived hepatocyte function

Christian Elabd, PhD | Abstract Presenter

Objectives

  • Recognize novel industry-developed therapeutic candidates in early-stage development for liver disease.