Therapeutic Strategies in MASH: Incretins, Metabolic Modulators, and Novel Approaches
Nov
2026
Description
This session will examine evolving therapeutic approaches for metabolic dysfunction-associated steatohepatitis, with emphasis on pharmacologic and mechanistic interventions targeting steatohepatitis, fibrosis, metabolic dysfunction, and cirrhosis. Together, these studies showcase the expanding treatment landscape for MASH across disease stages, fibrosis severity, cardiometabolic subgroups, and emerging therapeutic mechanisms.
Presentations
8:00 AM
- 8:15 AM
Convention Center - Bluebird Ballroom 1A
Impact of Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RA) on Metabolic Dysfunction associated Steatohepatitis (MASH) Cirrhosis.
Olufunso Agbalajobi, MD, MPH | Abstract Presenter
8:15 AM
- 8:30 AM
Convention Center - Bluebird Ballroom 1A
DR10624, a novel fibroblast growth factor 21 (FGF21), glucagon, and glucagon-like peptide-1 (GLP-1) receptors tri-agonist for metabolic dysfunction-associated steatohepatitis treatment
Yixuan Zhu | Abstract Presenter
8:30 AM
- 8:45 AM
Convention Center - Bluebird Ballroom 1A
Efficacy of survodutide treatment assessed by liver endpoints across weight-reduction category at end of treatment: results from a phase 2 trial of survodutide in people with metabolic dysfunction–associated steatohepatitis and fibrosis
Arun Sanyal | Abstract Presenter
8:45 AM
- 9:00 AM
Convention Center - Bluebird Ballroom 1A
Positive Phase 2b Clinical Results of Novel First-in-Class Pan-PDE Inhibitor ZSP1601: Safety, Antifibrotic and Metabolic Improvement in MASH Participants with F2/F3 Fibrosis
Jinlin Hou, MD | Abstract Presenter
9:00 AM
- 9:15 AM
Convention Center - Bluebird Ballroom 1A
Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in MASH Cirrhosis: A Multi-Dose Meta-Analysis
Farhan Murtaza, MD | Abstract Presenter
9:15 AM
- 9:30 AM
Convention Center - Bluebird Ballroom 1A
Electroacupuncture Attenuates Experimental MASLD via Neuroimmune Remodeling of Hepatic Macrophage Responses
Shangze Jiang, PhD | Abstract Presenter