Hepatotoxicity and Pediatric Liver Disorders Special Interest Groups Joint Symposium, Part 2. Drug-Induced Liver Injury: Emerging Trends in Drug-Induced Liver Injury—From Children to Adults

Description

Topic experts discuss the risk of DILI and phenotypes of presentation from children to the elderly. Presenters review emerging and novel therapies associated with DILI, provide an update on blood-based biomarkers of DILI, and highlight research priorities to address knowledge gaps in this constantly evolving space.

 

Presentations

5:00 PM - 5:15 PM
Nov 09 2025
Washington, D.C.

Using Spatial Multiomic Tools to Study Hepatotoxicity

Jonny Sexton, PhD, Presenter
Drug-Induced Liver Injury
Pediatrics
5:15 PM - 5:30 PM
Nov 09 2025
Washington, D.C.

Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome (DRESS): Mechanisms and Implicated Agents From Children to Adults

Elizabeth J Phillips, MD, Presenter
Drug-Induced Liver Injury
Pediatrics
5:30 PM - 5:45 PM
Nov 09 2025
Washington, D.C.

Hepatotoxicity Related to Novel Gene Therapy: Mechanisms and Clinical Implications

Tamir Diamond, MD, Presenter
Drug-Induced Liver Injury
Pediatrics
5:45 PM - 6:00 PM
Nov 09 2025
Washington, D.C.

Gaps in Knowledge and Future Directions in Drug-Induced Liver Injury

Robert J. Fontana, MD, FAASLD, Presenter
Drug-Induced Liver Injury
Pediatrics

Objectives

  • Recognize the different phenotypes of DILI and the predominant culprit agents in children and adults.
  • Identify the DILI risks associated with emerging and novel therapeutic agents.
  • Devise strategies to mitigate the risks, diagnose, and manage DILI across the lifespan.
Chair

Lily Dara, MD

University of Southern California
Chair

Samar H Ibrahim, MBCHB, FAASLD

Mayo Clinic Rochester