Planned in partnership with the American Gastroenterological Association and the American Society for Gastrointestinal Endoscopy, this update provides the hepatology specialist with guidance on the management of common gastrointestinal challenges when caring for patients with decompensated cirrhosis. Presenters review the latest evidence in the management of complex liver diseases including key challenges in endohepatology; management of large polyps; dual therapy in primary prophylaxis of variceal bleeding; and preoperative management of the patient with MASLD-induced cirrhosis.