Leila Gobejishvili

Biography

Leila Gobejishvili is Associate Professor in the Department of Physiology at the University of Louisville, Louisville, Kentucky. She received her PhD in Biology from the Institute of Physiology, Georgian Academy of Sciences, Tbilisi, Georgia in 1995. In 2001 she joined Dr. Craig McClain's liver research group. Her first project examined the mechanisms of alcohol mediated "priming" of monocytes/macrophages to produce higher levels of inflammatory cytokines in response to endotoxin. This work led her to study the role of cyclic nucleotide signaling in pathogenesis of alcohol-associated liver disease and fibrosis. Her current project investigates the mechanisms involved in the protection of alcohol induced liver injury and fibrosis by phosphodiesterase 4 (PDE4) inhibition.