Hepatology, cardiology, and transplant medicine experts discuss the pathophysiology, clinical management, and long-term outcomes of Fontan-associated liver disease. The symposium highlights emerging research, diagnostic advancements, and multidisciplinary approaches to improve surveillance, treatment, and transplant decision-making for this unique patient population. Audience members learn from persuasive arguments by transplant surgeons regarding the options of isolated heart transplant versus combined heart-liver transplant for pediatric patients with Fontan failure. Attendees participate in this discussion by questioning presenters and voting how they would handle a challenging clinical case in light of the information presented.