From Mice to Medicine: Decoding Alcohol Associated Liver Disease Pathways and Therapies

Nov 09 2025
Convention Center: Ballroom B, Level 3
11:00 AM - 12:30 PM

World Class Speakers

Frederick A Ekuban, Ph.D.
Abstract Presenter

Frederick A Ekuban, Ph.D.

University of Louisville
Michele Pritchard, PhD
Abstract Presenter

Michele Pritchard, PhD

University of Kansas Medical Center
Michele Pritchard, PhD
Moderator

Michele Pritchard, PhD

University of Kansas Medical Center
Gene Im, MD, FAASLD
Moderator

Gene Im, MD, FAASLD

Columbia University

Description

The abstracts presented in this session advance our understanding of alcohol-associated liver disease (ALD) through cutting-edge research utilizing both mouse and human models. The session highlights key mechanisms and mediators of ALD, including oxidative stress, inflammation, and the gut-liver axis. It also explores the interplay between the liver and adipose tissue, the impact of environmental factors, and the potential of GLP1 as a therapeutic target. The objective is to foster discussion and collaboration around these diverse yet interconnected pathways to inform future research and treatment strategies.

Journey Maps

ALD

Presentations

11:00 AM - 11:15 AM
Aug 06 2026
Convention Center - Ballroom B, Level 3

The role of TRAIP in alcohol-induced liver injury through regulating β-catenin ubiquitin degradation via direct interaction

Frederick A Ekuban, Ph.D. , Abstract Presenter
ALD
11:15 AM - 11:30 AM
Aug 06 2026
Convention Center - Ballroom B, Level 3

STING Knockdown Attenuates Alcoholic Liver Disease Progression via NLRP3-Mediated Pyroptosis Suppression

Michele Pritchard, PhD , Abstract Presenter
ALD
11:30 AM - 11:45 AM
Aug 06 2026
Convention Center - Ballroom B, Level 3

Environmental Forever Chemical Exposures Modify the Severity of Alcohol-Associated Liver Disease

Frederick A Ekuban, Ph.D. , Abstract Presenter
ALD
11:45 AM - 12:00 PM
Aug 06 2026
Convention Center - Ballroom B, Level 3

GLP-1 Dysregulation in Alcoholic Liver Disease: Elucidating Intestinal Mechanisms Affected by Chronic Alcohol Abuse

Frederick A Ekuban, Ph.D. , Abstract Presenter
ALD
12:00 PM - 12:15 PM
Aug 06 2026
Convention Center - Ballroom B, Level 3

Targeting GLP-1 and GCG Receptors as Potential Therapeutic Approaches for Alcohol-associated Liver Disease: Focusing on the Role of the Liver-Gut Axis

Michele Pritchard, PhD , Abstract Presenter
ALD
12:15 PM - 12:30 PM
Aug 06 2026
Convention Center - Ballroom B, Level 3

Adipocyte miR-150 Deficiency Ameliorates Alcohol-Induced Liver Injury by Promoting Adipose Tissue Browning 

Frederick A Ekuban, Ph.D. , Abstract Presenter
ALD

Objectives

  • Identify the potential mechanisms of oxidative stress in alcohol associated liver disease (ALD).
  • Describe the underlying mechanisms of GLP1 as a potential therapeutic target in ALD.
  • Discuss the potential role for environmental exposures in ALD.