Speakers provide updates on novel herbal and dietary supplements that may potentially cause liver injury, including but are not limited to green tea extracts, curcumin/turmeric, ashwagandha, kratom, black cohosh, garcinia cambogia, and red yeast extract. Topics include specific signatures and patterns of liver enzymes associated with liver injury due to ingestion of selected herbal compounds and over-the-counter medications, and compounds that are considered to present minimal risk for DILI.