CXCR3+ monocyte-derived macrophages contribute to congestive portal hypertension through the glycolysis-dependent synthesis of vasoactive molecules: insights from multiomics
Yasuko Iwakiri, PhD, FAASLD
, Abstract Presenter
Cirrhosis and Portal Hypertension
5:15 PM
- 5:30 PM
Aug
06
2026
Convention Center - Room 202, Level 2
Pressure‑induced endothelial fibulin‑7 modulates HSC phenotype and lowers portal pressure in experimental cirrhosis
Justin Boike, MD, MPH
, Abstract Presenter
Cirrhosis and Portal Hypertension
5:30 PM
- 5:45 PM
Aug
06
2026
Convention Center - Room 202, Level 2
Direct FXa-Inhibitor Edoxaban improves portal hypertension in experimental toxic and metabolic fibrosis models
Yasuko Iwakiri, PhD, FAASLD
, Abstract Presenter
Cirrhosis and Portal Hypertension
5:45 PM
- 6:00 PM
Aug
06
2026
Convention Center - Room 202, Level 2
INHIBITION OF H2S PRODUCTION REDUCES PORTAL PRESSURE BY DECREASING INTRAHEPATIC RESISTANCE IN RATS WITH CIRRHOSIS
Justin Boike, MD, MPH
, Abstract Presenter
Cirrhosis and Portal Hypertension
6:00 PM
- 6:15 PM
Aug
06
2026
Convention Center - Room 202, Level 2
Dysfunctional Kynurenine metabolism promotes neuroinflammation during hepatic encephalopathy development
Yasuko Iwakiri, PhD, FAASLD
, Abstract Presenter
Cirrhosis and Portal Hypertension
6:15 PM
- 6:30 PM
Aug
06
2026
Convention Center - Room 202, Level 2
Crucial role for albumin to rescue impaired B cell function and viability in patients with acutely decompensated cirrhosis
Justin Boike, MD, MPH
, Abstract Presenter
Cirrhosis and Portal Hypertension
Objectives
Describe recent experimental and translational discoveries related to complications of cirrhosis, including portal hypertension and hepatic encephalopathy.