This focused session brings together experienced hepatology researchers to share insights on the critical elements of building a successful research career, whether pursuing a clinician-investigator or academic researcher path. Through 3 comprehensive lectures and an interactive panel discussion, participants learn essential strategies for establishing mentorship relationships, conducting impactful clinical research, and navigating the academic timeline. For clinicians maintaining busy practices, speakers address practical approaches to integrating research activities within clinical responsibilities, including strategies for protected research time and efficient study execution. For those pursuing dedicated academic research careers, the session covers establishing independent research programs, securing sustained funding, and building research teams. The session features leading experts who share their personal experiences and practical advice from both career paths, followed by an open forum where attendees can engage directly with speakers to address specific questions about research career development in hepatology.