MTE #1: Acute-on-Chronic Liver Failure at the Crossroads—High-Stakes Decisions in Critical Care, Advanced Organ Support, and Palliation (Ticketed)

Managing acute-on-chronic liver failure (ACLF) in the intensive care unit often involves navigating some of the most complex and ethically charged decisions in hepatology and critical care. Experts explore the pivotal moments when clinicians must decide whether to escalate aggressive organ support or transition toward palliative approaches. Presenters share evidence-based strategies for advanced multiorgan support—including renal replacement therapy, vasopressor management, and ventilatory support—while addressing the nuances of transplant candidacy and futility assessment. Faculty also highlight emerging technologies, evolving ethical considerations, and practical tools for guiding conversations with families and multidisciplinary teams. Through real-world case discussions, participants gain insight into balancing survival benefit against resource limitations, integrating patient values, and applying consensus frameworks under time pressure.