Experts provide an overview of the latest innovations in study design in MetALD-induced liver disease, including study endpoints. Presenters explore how to design and conduct effective cohort studies, large database studies, and clinical trials. Topics include the role of investigator-initiated cohort studies, large national database studies, and clinical trials in MetALD with discussion of funding opportunities, monitoring, and conducting these studies with a focus on early-stage investigators. This interactive session provides an opportunity to discuss study methodologies, existing studies, and protocols with the moderators.