MTE #23 The "GENIE" in the Hepatitis B Bottle: What's New in Genetic Modulation for Hepatitis B Cure?

Nov 09 2025
Convention Center: Room 140B, Level 1
12:45 PM - 1:30 PM
Ticketed Event

World Class Speakers

Edward J Gane, MD, FAASLD
Discussion Leader

Edward J Gane, MD, FAASLD
Barbara Testoni, PhD
Discussion Leader

Barbara Testoni, PhD

Inserm UMR 1350, University of Lyon 1, IHU EVEREST

Description

Discover the latest advances towards a functional cure of HBV infection. Experts present information about the latest clinical and basic studies exploring gene editing therapy, epigenetic modulation such as gene silencing using CRISPR/Cas9, and viral genetic targets such as antisense oligonucleotide (ASO) and small interfering RNA (siRNA). Experts and participants discuss these topics in the context of the prospect of a hepatitis B cure.

 

Journey Maps

Objectives

  • Describe the potential role of gene editing therapy for HBV infection.
  • Explain the principles of epigenetic modulation as a strategy for hepatitis B cure.
  • Discuss the potential role of translation inhibitors (eg, antisense oligonucleotides and small interfering RNA) to achieve hepatitis B cure.