Dr. Constantine (Dean) Karvellas is a Professor of Critical Care Medicine at the University of Alberta and an Adjunct Professor in the School of Public Health Sciences. He has been an attending intensivist in the E. Garner King General Systems Intensive Care Unit since 2009 and is involved with the Liver Transplant program as a Hepatologist. Dr. Karvellas is the only Canadian co-investigator in the NIH-funded United States Acute Liver Failure study group (US ALFSG). He is an Associate Editor for the Journal of Hepatology and a co-chair of the American Association for the Study of Liver Diseases (AASLD) Acute on chronic liver failure Guidance. Dr. Karvellas has over 180 publications reflecting his interests in acute liver failure (ALF), acute on chronic liver failure (ACLF), liver transplantation and extracorporeal liver support.