Basic Science Symposium, Parts 1–4: Protein Quality Control, the Unfolded Protein Response, and Endoplasmic Reticulum Stress in Acute and Chronic Liver Disease
Nov
2026
World Class Speakers
Description
This basic science symposium explores the fundamentals of and latest advances in endoplasmic reticulum (ER) stress and proteostasis in the pathophysiology of liver injury and chronic liver disease. Potential opportunities for translation of these advances into novel therapeutics are also explored.
Part 1: Fundamentals of the Unfolded Protein Response and Endoplasmic Reticulum Stress
Part 2: Endoplasmic Reticulum Stress in the Pathophysiology of Liver Injury
Part 3: Endoplasmic Reticulum Stress in the Progression of Chronic Liver Disease
Part 4: Bench to Bedside—Opportunities for Therapeutic Targeting of the Unfolded Protein Response and Endoplasmic Reticulum Stress in Acute and Chronic Liver Disease
Presentations
8:00 AM
- 8:20 AM
Convention Center - Bluebird Ballroom 1A
Overview of the Unfolded Protein Response and Endoplasmic Reticulum Stress in Liver Disease
Randal J Kaufman, PHD | Presenter
8:20 AM
- 8:40 AM
Convention Center - Bluebird Ballroom 1A
Endoplasmic Reticulum–Mitochondria Contacts and Crosstalk
Marc S Sherman, MD, PhD | Presenter
8:40 AM
- 9:00 AM
Convention Center - Bluebird Ballroom 1A
Endoplasmic Reticulum Stress and Metabolism
Tom Rutkowski, PhD | Presenter
10:15 AM
- 10:35 AM
Convention Center - Bluebird Ballroom 1A
Liver Injury and Inflammation
Harmeet Malhi, MBBS, FAASLD | Presenter
10:35 AM
- 10:55 AM
Convention Center - Bluebird Ballroom 1A
Lipid Droplets and Endoplasmic Reticulum Stress
Will Prinz, Ph.D. | Presenter
10:55 AM
- 11:15 AM
Convention Center - Bluebird Ballroom 1A
Endoplasmic Reticulum Stress and Autophagy
Wen-Xing Ding, MD, PhD, FAASLD | Presenter
1:05 PM
- 1:25 PM
Convention Center - Bluebird Ballroom 1A
Endoplasmic Reticulum Stress and the Liver-Pituitary Axis in Chronic Liver Disease
Ling Yang, PhD | Presenter
1:25 PM
- 1:45 PM
Convention Center - Bluebird Ballroom 1A
Endoplasmic Reticulum Stress in Fibrosis
Jessica Maiers, PhD | Presenter
1:45 PM
- 2:05 PM
Convention Center - Bluebird Ballroom 1A
Endoplasmic Reticulum Stress in Hepatocellular Carcinoma
Michael Karin, PhD | Presenter
3:15 PM
- 3:35 PM
Convention Center - Bluebird Ballroom 1A
Novel Therapeutics for Alpha-1 Antitrypsin Deficiency
Pavel Strnad | Presenter
3:35 PM
- 3:55 PM
Convention Center - Bluebird Ballroom 1A
Endoplasmic Reticulum Stress as a Potential Target in Cholestatic Liver Disease
Alyssa Kriegermeier, MD | Presenter
3:55 PM
- 4:15 PM
Convention Center - Bluebird Ballroom 1A
Endoplasmic Reticulum Stress as a Potential Target in Metabolic Dysfunction–Associated Steatotic Liver Disease
Béatrice Bailly-Maitre, Ph.D | Presenter
