Current Therapeutic Strategies in MASH: Lifestyle and Pharmacologic Interventions

Description

This session examines pharmacologic (GLP-1 agonists, resmetirom) and lifestyle-based interventions for MASH/MASLD across adult and pediatric populations, including transplant recipients.

Presentations

11:00 AM - 11:15 AM
Convention Center - Bluebird Ballroom 1A
Recorded session

Semaglutide and Fibrosis Progression in MASLD: A Target Trial Emulation Comparing Semaglutide Versus DPP-4 Inhibitors in a National Cohort

Binu V. John | Abstract Presenter
11:15 AM - 11:30 AM
Convention Center - Bluebird Ballroom 1A
Recorded session

Buttermilk Supplementation Ameliorates Hepatic Steatosis in Metabolic Dysfunction Associated Steatotic Liver Disease

Sukriti Baweja, PhD | Abstract Presenter
11:30 AM - 11:45 AM
Convention Center - Bluebird Ballroom 1A
Recorded session

Impact of Multidisciplinary Care on Longitudinal ALT Outcomes in Children With MASLD

Brandon Perumpail, MD | Abstract Presenter
11:45 AM - 12:00 PM
Convention Center - Bluebird Ballroom 1A
Recorded session

Semaglutide Improves Liver Health in Non‑Obese Participants With MASH: A Post Hoc Analysis From the Phase 3 ESSENCE Trial

Jörn M Schattenberg, MD, | Abstract Presenter
12:00 PM - 12:15 PM
Convention Center - Bluebird Ballroom 1A
Recorded session

GLP-1 Receptor Agonist Use After Liver Transplantation in MASH or Metabolic-Risk Recipients Is Associated With Improved Survival and Renal Protection: A Three-Center Cohort Study

Zhihao Li, MD | Abstract Presenter
12:15 PM - 12:30 PM
Convention Center - Bluebird Ballroom 1A
Recorded session

Structured Lifestyle Intervention Based on Cognitive-Behavioral Therapy Principles Reduces Hepatic Steatosis and Improves Metabolic Parameters in Patients with MASLD: Preliminary Results of a Randomized Controlled Study

Vaclav Smid, Assoc.Prof., MD, PhD | Abstract Presenter

Objectives

  • Analyze clinical trial data for approved and late-stage MASH therapies
  • Discuss the implications of a structured comprehensive program in MASH management, focusing on both foundational lifestyle modifications and the evolving landscape of targeted pharmacotherapy
  • Analyze the efficacy, safety, and appropriate patient selection for recently approved medications (e.g., resmetirom) and emerging therapies (e.g., GLP-1/GIP agonists)