Applications of Real-World Data in Clinical Practice  

Nov 08 2025
Convention Center: Room 146A, Level 1
11:00 AM - 12:30 PM

World Class Speakers

Nadim Mahmud, MD, MS, MPH, MSCE
Presenter

Nadim Mahmud, MD, MS, MPH, MSCE

Hospital of the University of Pennsylvania
Douglas A. Simonetto, MD
Presenter

Douglas A. Simonetto, MD

Mayo Clinic Rochester
Jasmohan S. Bajaj, MD, FAASLD
Presenter

Jasmohan S. Bajaj, MD, FAASLD

Virginia Commonwealth University
Alastair J O'Brien, MD
Presenter

Alastair J O'Brien, MD

University College London
Louise China, MBBS, PhD
Presenter

Louise China, MBBS, PhD

UCL Institute of Hepatology
Nicole J Kim, MD, MPH
Moderator

Nicole J Kim, MD, MPH

University of Washington
Albert Do, MD, MPH
Moderator

Albert Do, MD, MPH

UC Davis

Description

Presenters explore commonly encountered clinical scenarios where practice patterns are variable and consensus is often lacking on the appropriate application of guidelines. Experts offer insights from real-world experience and large-scale data to generate consensus on the best clinical practices in the following scenarios: applying portal hypertension guidance to individual patients; improving surgical risk stratification; rethinking spontaneous bacterial peritonitis prophylaxis; and optimizing use of albumin and terlipressin.

Journey Maps

Presentations

11:00 AM - 11:15 AM
Nov 08 2025
Washington, D.C.

Optimizing Preoperative and Surgical Care for Patients With Cirrhosis: A Case-Based Approach

Nadim Mahmud, MD, MS, MPH, MSCE, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
11:15 AM - 11:30 AM
Nov 08 2025
Washington, D.C.

Applying Portal Hypertension Guidance to Real-World Practice: A Case-Based Approach

Douglas A. Simonetto, MD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
11:30 AM - 11:45 AM
Nov 08 2025
Washington, D.C.

Debate: Is It Time to Rethink Spontaneous Bacterial Peritonitis Prophylaxis? (PRO)

Jasmohan S. Bajaj, MD, FAASLD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
11:45 AM - 12:00 PM
Nov 08 2025
Washington, D.C.

Debate: Is It Time to Rethink Spontaneous Bacterial Peritonitis Prophylaxis? (CON)

Alastair J O'Brien, MD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
12:00 PM - 12:15 PM
Nov 08 2025
Washington, D.C.

Optimal Use of Albumin and Terlipressin: Translating Clinical Trials Into Practice

Louise China, MBBS, PhD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
12:15 PM - 12:30 PM
Nov 08 2025
Washington, D.C.

Panel Discussion

Albert Do, MD, MPH, Moderator
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant

Objectives

  • Describe noninvasive assessment of portal hypertension.
  • Review indications for nonselective beta-blocker prophylaxis.
  • Summarize the appropriateness of endoscopy for screening and surveillance of esophageal varices.
  • Identify evidence-based strategies to estimate surgical risk for patients with cirrhosis.
  • Explain the use of albumin and terlipressin by reviewing recent pivotal trials and real-world evidence.
Chair

Hersh Shroff, MD, MPA

UNC Chapel Hill
Chair

Marina Serper, MD, MS

University of Pennsylvania Health System