Applications of Real-World Data in Clinical Practice  

Description

Presenters explore commonly encountered clinical scenarios where practice patterns are variable and consensus is often lacking on the appropriate application of guidelines. Experts offer insights from real-world experience and large-scale data to generate consensus on the best clinical practices in the following scenarios: applying portal hypertension guidance to individual patients; improving surgical risk stratification; rethinking spontaneous bacterial peritonitis prophylaxis; and optimizing use of albumin and terlipressin.

Presentations

11:00 AM - 11:15 AM
Nov 08 2025
San Diego, CA

Optimizing Preoperative and Surgical Care for Patients With Cirrhosis: A Case-Based Approach

Nadim Mahmud, MD, MS, MPH, MSCE, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
11:15 AM - 11:30 AM
Nov 08 2025
San Diego, CA

Applying Portal Hypertension Guidance to Real-World Practice: A Case-Based Approach

Douglas A. Simonetto, MD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
11:30 AM - 11:45 AM
Nov 08 2025
San Diego, CA

Debate: Is It Time to Rethink Spontaneous Bacterial Peritonitis Prophylaxis?

Jasmohan S. Bajaj, MD, FAASLD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
11:45 AM - 12:00 PM
Nov 08 2025
San Diego, CA

Optimal Use of Albumin and Terlipressin: Translating Clinical Trials Into Practice

Louise China, MBBS, PhD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
11:45 AM - 12:00 PM
Nov 08 2025
San Diego, CA

Debate: Is It Time to Rethink Spontaneous Bacterial Peritonitis Prophylaxis?

Alastair J O'Brien, MD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant
12:00 PM - 12:30 PM
Nov 08 2025
San Diego, CA

Panel Discussion

Nadim Mahmud, MD, MS, MPH, MSCE, Panelist
Acute Liver Failure
Acute-on-Chronic Liver Failure
ALD
Cirrhosis and Portal Hypertension
DEI
Drug-Induced Liver Injury
Hepatitis
Liver Cancer
MASLD
Pediatrics
Trainee
Transplant

Objectives

  • Describe noninvasive assessment of portal hypertension.
  • Review indications for nonselective beta-blocker prophylaxis.
  • Summarize the appropriateness of endoscopy for screening and surveillance of esophageal varices.
  • Identify evidence-based strategies to estimate surgical risk for patients with cirrhosis.
  • Explain the use of albumin and terlipressin by reviewing recent pivotal trials and real-world evidence.
Chair

Hersh Shroff, MD, MPA

UNC Chapel Hill
Chair

Marina Serper, MD, MS

University of Pennsylvania Health System