Cellular and Molecular Drivers of Liver Homeostasis, Injury, and Regeneration
Nov
2026
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This session highlights cutting-edge discoveries in liver biology and disease, showcasing novel molecular mechanisms that regulate liver cell identity, injury responses, fibrosis, bile acid metabolism, and regeneration. Presentations explore innovative therapeutic approaches, including exosome-based delivery systems, machine learning–driven cell engineering, and pharmacologic modulation of regenerative pathways, that advance our understanding of liver homeostasis and repair.
Presentations
11:00 AM
- 11:15 AM
Convention Center - Bluebird Ballroom 2DEF
DFNA5-mediated secondary necrosis promotes TNF/NF-κB signaling during hepatocarcinogenesis
Tomoya Hamabe, MD | Abstract Presenter
11:15 AM
- 11:30 AM
Convention Center - Bluebird Ballroom 2DEF
Constitutive c-Maf expression via adenoviral delivery enables three-dimensional culture of LSEC like cells in vitro.
Jesus Maria M Gomez Salinero, PhD | Abstract Presenter
11:30 AM
- 11:45 AM
Convention Center - Bluebird Ballroom 2DEF
Geometry-Tuned Primary Human Hepatocyte Culture Defines a Mechanotransduction Set Point for Hepatocyte Identity Loss
Takeshi Saito, MD, PhD | Abstract Presenter
11:45 AM
- 12:00 PM
Convention Center - Bluebird Ballroom 2DEF
Hepatic X-box binding protein 1 (XBP1) regulates the bile acid synthetic enzyme cholesterol 7 alpha-hydroxylase (CYP7A1) in the liver
Xiaoying Liu | Abstract Presenter
12:00 PM
- 12:15 PM
Convention Center - Bluebird Ballroom 2DEF
FXR and PPAR ligands reveal Potential Pharmacological Crosstalk with MRGPRX4 in Hepatobiliary Pruritus
Silvia M Pickering | Abstract Presenter
12:15 PM
- 12:30 PM
Convention Center - Bluebird Ballroom 2DEF
Apalutamide and Enzalutamide Promote Liver Regeneration and Attenuate Cholestatic Injury Through CAR/PXR Activation
Meina Cai, MD | Abstract Presenter
