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Learning objectives In this Back to Basics series, the learner will be able to : Explain the role of ammonia in physiological changes in hepatic encephalopathy (HE) Formulate a diagnostic approach for...

Learning Objectives In this Back to Basics series post, the learner will be able to: Review outpatient management of portal hypertension-related complications and hepatic encephalopathy. Learn who and...

Brief Case Presentation This is a case of an intraoperative consultation for donor liver evaluation. The donor passed away due to congestive heart failure, with no significant oncological history...

Introduction Primary sclerosing cholangitis (PSC) is a heterogenous and progressive disease of the biliary tree, resulting in fibrosis and the eventual development of cirrhosis. Due to recurrent...

What is Hepatitis Delta Virus? HDV is a single-stranded RNA virus that depends on the presence of Hepatitis B virus (HBV) to enter and exit hepatocytes and sustain its replication. The HDV genome...

Ascites is a common complication of cirrhosis secondary to hemodynamic changes that cause systemic and splenic vasodilation as result of increased nitric oxide. The presence of ascites is associated...