AASLD develops evidence-based practice guidelines, practice guidances, and patient guidances to share recommended approaches to the diagnostic, therapeutic, and preventive aspects of care. View the AASLD Policy here.
AASLD guidelines use clinically relevant questions, which are then answered by systematic reviews of the literature, and followed by data-supported recommendations. The guidelines are developed by a multidisciplinary panel of experts who rate the quality (level) of the evidence and the strength of each recommendation using the Grading of Recommendations Assessment, Development, and Evaluation system.
AASLD guidance statements are put forward to help clinicians understand and implement the most recent evidence based on comprehensive review and analysis of the literature. Recently AASLD has published guidances on aspects of a topic that lacked sufficient data to perform systematic reviews.
AASLD also develops quality measures to help its members measure or quantify healthcare processes and outcomes that are associated with the ability to provide high-quality health care. AASLD’s Cirrhosis Quality Collaborative network combines quality improvement and research to improve the care and treatment outcomes of patients with cirrhosis.
Read more about practice guideline development and about AASLD’s conflict of interest policy in articles excerpted from the Hepatology Journal, or review AASLD's Code for the Assessment and Management of Conflict of Interest.
Guidelines and Guidance by Disease
- Acute Liver Failure, Management
- Alcohol-Associated Liver Disease
- Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome, Management
- Autoimmune Hepatitis, Management
- Drug, Herbal, and Dietary Supplement-induced Liver Injury
- Hemochromatosis, Management
- Hepatic Encephalopathy
- Hepatitis B, Chronic
- Hepatitis C, Guidance
- Hepatocellular Carcinoma, Management
- Liver Biopsy
- Liver Transplantation, Evaluation of the Adult Patient
- Liver Transplantation, Evaluation of the Pediatric Patient
- Long-Term Management of the Adult Liver Transplant
- Long-Term Management of the Pediatric Liver Transplant
- Malnutrition, Frailty, and Sarcopenia in Patients with Cirrhosis
- Non-Alcoholic Fatty Liver Disease, Diagnosis and Management
- Palliative Care and Symptom-Based Management for Decompensated Cirrhosis
- Portal Hypertension Bleeding in Cirrhosis, Guidance
- Portal Hypertension, Management and Tips
- Primary Biliary Cholangitis
- Primary Sclerosing Cholangitis and Cholangiocarcinoma
- Reproductive Health and Liver Disease
- Vascular Disorders of the Liver
- Wilson Disease, Diagnosis and Treatment
Guidelines and Guidances in Development
AASLD strives to review and update its practice guidelines every five (5) years, as necessary. Users are cautioned that in the interim, scientific and medical developments may supersede or invalidate, in whole or in part, specific recommendations in any guideline. A guideline is considered to be "inactive" if it has not been updated by AASLD in at least five (5) years, and for this reason particular care must be exercised in placing reliance on an inactive guideline.
AASLD commissions and provides financial support for the formulation and production of practice guidelines/guidances by volunteer experts. Financial support from commercial entities or the pharmaceutical industry is not accepted for the development of AASLD practice guidelines or guidances.
The following practice guidelines and guidances are in development:
- Non-Invasive Liver Disease Assessment
- Acute on Chronic Liver Failure/ICU Care
- Hepatocellular Carcinoma
- Non-Alcoholic Fatty Liver Disease
- Portal Hypertension in Cirrhosis
- Role of TIPS, BRTO, BATO, BATO in Gastroesophageal varices
- Wilson Disease
Quality measures are a tool for providers and institutions to evaluate their care quality, drive quality improvement, and deliver high-value patient care.View Quality Measures
Patient Guidances are adaptations of published AASLD guidances which are written specifically for patients to help them understand their liver disease. Clinicians may also provide these patient guidances to their patients as a resource during consultations.View Patient Guidelines
Citing Practice Guidelines and Guidances
AASLD practice guidelines and guidances are copyright protected. One copy may be accessed for personal research, scientific, scholarly or informational purposes and may be transmitted to a third-party colleague in hard copy or electronically for similar use. One figure, table or brief excerpt less than 400 words may be used in one’s scientific, scholarly and educational work with appropriate credit.
Permission is required to reproduce more than one figure, table, or section over 400 words or complete practice guidelines and guidances for systematic redistribution. Re-sale and posting AASLD practice guidelines and guidances on other websites are not allowed; however, linking to these documents is permitted. Contact firstname.lastname@example.org for assistance.