Liver Cell Biology In Hepatic Diseases

The mission of the Liver Cell Biology in Hepatic Diseases SIG is to advance and disseminate the science and practice of hepatology, and to promote liver health and quality patient care.

Activity Goals And Objectives

Gain a greater understanding of basic cell biological functions of hepatic cells such as protein/lipid traffic, cytoskeletal organization, cellular polarity and receptor signaling cascades in health and disease. Pathological changes in cellular functions can translate into modulation of trafficking, cell adhesion and matrix production leading to liver damage, cholestasis and fibrogenic signals.

Understand how the central processes listed above are altered and tailored to suit the highly specialized functions of the liver including regeneration, bile formation, secretion of essential plasma proteins, identification of biomarkers of disease progression and regulation of extracellular matrix turnover.

Identify how hepatocellular functions are altered during hepatic diseases such as liver fibrosis and cancer.

SIG Leadership

Chairs
Kari Nejak-Bowen, MBA, PhD
Wen-Xing Ding, MD, PhD, FAASLD
Communication Lead
Bilon Khambu, MSc, PhD
Education Lead
Takahiro Kodama, MD, PhD
Trainee Lead
Kyle Yuquimpo, DO
Staff Liaisons
Akuender Dot, MPH
Julie Hoffman, MBA
At-Larges
Matthew A. Burchill, PhD
Jordi Gracia-Sancho, PhD, FAASLD
Enis Kostallari, PhD, MS
Mengfei Liu, MD
Jessica Maiers, PhD