Liver Cell Biology In Hepatic Diseases

The mission of the Liver Cell Biology in Hepatic Diseases SIG is to advance and disseminate the science and practice of hepatology, and to promote liver health and quality patient care.

Activity Goals And Objectives

Gain a greater understanding of basic cell biological functions of hepatic cells such as protein/lipid traffic, cytoskeletal organization, cellular polarity and receptor signaling cascades in health and disease. Pathological changes in cellular functions can translate into modulation of trafficking, cell adhesion and matrix production leading to liver damage, cholestasis and fibrogenic signals.

Understand how the central processes listed above are altered and tailored to suit the highly specialized functions of the liver including regeneration, bile formation, secretion of essential plasma proteins, identification of biomarkers of disease progression and regulation of extracellular matrix turnover.

Identify how hepatocellular functions are altered during hepatic diseases such as liver fibrosis and cancer.

SIG Leadership

Satdarshan (Paul) Singh Monga, MD, FAASLD

Kari Nejak-Bowen, MBA, PhD

Olivier Barbier, PhD, FAASLD

Staff Liaisons
Patricia Marshall
Akuender Dot
Linda Howard

Steering Committee Members
Timothy Caminata, Jr., Msn
Yasuko Iwakiri, PhD, FAASLD
Leila Gobejishvili, PhD
Wajahat Z. Mehal, MD, FAASLD
Jordi Gracia-Sancho, PhD
Jose Cordoba Chacon, PhD
Matthew A. Burchill, PhD
Mengfei Liu, MD
Enis Kostallari, PhD
Jessica Maiers, PhD