Mending the Model for End‐Stage Liver Disease: An in‐depth review of the past, present, and future portopulmonary hypertension Model for End‐Stage Liver Disease exception

Hilary M. DuBrock, Kathryn T. Valle, Michael J. Krowka – 1 February 2022 – Patients with portopulmonary hypertension (POPH) have an increased cardiovascular and overall mortality risk when undergoing liver transplantation (LT). However, such risk is not captured in their Model for End‐Stage Liver Disease (MELD) laboratory score. POPH MELD exception criteria were established in 2006 with the aim of prioritizing these patients for LT prior to pulmonary hypertension (PH) progression and eventual right heart failure.

Cerium oxide nanoparticles administration during machine perfusion of discarded human livers: A pilot study

Serena Del Turco, Valentina Cappello, Christos Tapeinos, Aldo Moscardini, Laura Sabatino, Matteo Battaglini, Fabio Melandro, Francesco Torri, Caterina Martinelli, Serena Babboni, Beatrice Silvestrini, Riccardo Morganti, Mauro Gemmi, Paolo De Simone, Paulo N. Martins, Laura Crocetti, Adriano Peris, Daniela Campani, Giuseppina Basta, Gianni Ciofani, Davide Ghinolfi – 30 January 2022 – The combined approach of ex situ normothermic machine perfusion (NMP) and nanotechnology represents a strategy to mitigate ischemia/reperfusion injury in liver transplantation (LT).

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