Expression of X protein and hepatitis B virus replication in chronic hepatitis
Yoshimichi Haruna, Norio Hayashi, Kazuhiro Katayama, Nobukabu Yuki, Akinori Kasahara, Yutaka Sasaki, Hideyuki Fusamoto, Takenobu Kamada – 1 March 1991 – The X protein can act on the enhancer of hepatitis B virus in an in vitro system and elevate the transcriptional level of hepatitis B virus. However, because no relationship had been reported between X protein expression and hepatitis B virus replication in patients with chronic hepatitis B, we focused on its expression in the liver in comparison with markers of hepatitis B virus replication.