Associations Between Prediagnostic Concentrations of Circulating Sex Steroid Hormones and Liver Cancer Among Postmenopausal Women

Jessica L. Petrick, Andrea A. Florio, Xuehong Zhang, Anne Zeleniuch‐Jacquotte, Jean Wactawski‐Wende, Stephen K. Van Den Eeden, Frank Z. Stanczyk, Tracey G. Simon, Rashmi Sinha, Howard D. Sesso, Catherine Schairer, Lynn Rosenberg, Thomas E. Rohan, Mark P. Purdue, Julie R. Palmer, Martha S. Linet, Linda M. Liao, I‐Min Lee, Jill Koshiol, Cari M. Kitahara, Victoria A. Kirsh, Jonathan N. Hofmann, Chantal Guillemette, Barry I. Graubard, Edward Giovannucci, J. Michael Gaziano, Susan M. Gapster, Neal D. Freedman, Lawrence S. Engel, Dawn Q. Chong, Yu Chen, Andrew T. Chan, Patrick Caron, Julie E.

Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans

Mirko E. Minniti, Matteo Pedrelli, Lise‐Lotte Vedin, Anne‐Sophie Delbès, Raphaël G.P. Denis, Katariina Öörni, Claudia Sala, Chiara Pirazzini, Divya Thiagarajan, Harri J. Nurmi, Markus Grompe, Kevin Mills, Paolo Garagnani, Ewa C.S. Ellis, Stephen C. Strom, Serge H. Luquet, Elizabeth M. Wilson, John Bial, Knut R. Steffensen, Paolo Parini – 30 November 2019

Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post–Liver Transplant Outcomes

Giuseppe Cullaro, Elizabeth C. Verna, Brian P. Lee, Jennifer C. Lai – 29 November 2019 – The burden of chronic kidney disease (CKD) is rising among patients with cirrhosis, though it is not known what impact this has had on outcomes after liver transplantation (LT). All patients listed for LT in the United States between 2002 and 2017 were analyzed, excluding those listed with Model for End‐Stage Liver Disease (MELD) exceptions. The primary outcome was post‐LT mortality.

The North American Consortium for the Study of End‐Stage Liver Disease–Acute‐on‐Chronic Liver Failure Score Accurately Predicts Survival: An External Validation Using a National Cohort

Russell Rosenblatt, Nicole Shen, Zaid Tafesh, Shirley Cohen‐Mekelburg, Carl V. Crawford, Sonal Kumar, Catherine Lucero, Robert S. Brown, Arun Jesudian, Brett E. Fortune – 29 November 2019 – Acute‐on‐chronic liver failure (ACLF) carries high short‐term mortality. The North American Consortium for the Study of End‐Stage Liver Disease (NACSELD)–ACLF score, positive if ≥2 organ failures are present, is a bedside tool that predicts short‐term mortality in patients with cirrhosis.

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