Liver Injury in Patients With Cholestatic Liver Disease Treated With Obeticholic Acid
John E. Eaton, Raj Vuppalanchi, Rajender Reddy, Sanjaya K. Satapathy, Bilal Ali, Patrick S. Kamath – 4 November 2019
Deficiency in Embryonic Stem Cell Marker Reduced Expression 1 Activates Mitogen‐Activated Protein Kinase Kinase 6–Dependent p38 Mitogen‐Activated Protein Kinase Signaling to Drive Hepatocarcinogenesis
Steve T. Luk, Kai‐Yu Ng, Lei Zhou, Man Tong, Tin‐Lok Wong, Huajian Yu, Chung‐Mau Lo, Kwan Man, Xin‐Yuan Guan, Terence K. Lee, Stephanie Ma – 4 November 2019
Liver Fat and Cardiometabolic Risk Factors Among School‐Age Children
Madelon L. Geurtsen, Susana Santos, Janine F. Felix, Liesbeth Duijts, Meike W. Vernooij, Romy Gaillard, Vincent W.V. Jaddoe – 4 November 2019
Reply:
Kaveh Hajifathalian, Babak Torabi Sagvand, Arthur McCullough – 4 November 2019
Liver Injury in Patients With Cholestatic Liver Disease Treated With Obeticholic Acid
John E. Eaton, Raj Vuppalanchi, Rajender Reddy, Sanjaya K. Satapathy, Bilal Ali, Patrick S. Kamath – 4 November 2019
Letter to the Editor: Modest Alcohol Consumption and Nonalcoholic Fatty Liver Disease: An Oxymoron?
Alain Braillon – 4 November 2019
Something Wicked this Way Comes
Timucin Taner, Julie K. Heimbach – 4 November 2019
A Pilot Genome‐Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH
Samer Gawrieh, Xiuqing Guo, Jingyi Tan, Marie Lauzon, Kent D. Taylor, Rohit Loomba, Oscar W. Cummings, Sreekumar Pillai, Pallav Bhatnagar, Kris V. Kowdley, Katherine Yates, Laura A. Wilson, Yii‐Der Ida Chen, Jerome I. Rotter, Naga Chalasani, NASH Clinical Research Network – 3 November 2019 – A significantly higher proportion of patients with nonalcoholic steatohepatitis (NASH) who received obeticholic acid (OCA) had histological improvement relative to placebo in the FLINT (farnesoid X nuclear receptor ligand obeticholic acid for noncirrhotic, NASH treatment) trial.
Self‐Renewal Capability of Hepatocytic Parental Progenitor Cells Derived From Adult Rat Liver Is Maintained Long Term When Cultured on Laminin 111 in Serum‐Free Medium
Junichi Kino, Norihisa Ichinohe, Masayuki Ishii, Hiromu Suzuki, Toru Mizuguchi, Naoki Tanimizu, Toshihiro Mitaka – 2 November 2019 – In this study, we investigated how the ability of hepatocytic parental progenitor cells (HPPCs) to self‐renew can be maintained and how laminin (LN) isoforms play an important role in their self‐renewal and maturation. Hepatocytes isolated from adult rat livers were cultured on hyaluronic acid to form colonies consisting of CD44+ small hepatocytes, which could be passaged on dishes coated with Matrigel.
Serum Bioavailable, Rather Than Total, 25‐hydroxyvitamin D Levels Are Associated With Hepatocellular Carcinoma Survival
Ai‐Ping Fang, Jing‐An Long, Yao‐Jun Zhang, Zhao‐Yan Liu, Qi‐Jiong Li, Dao‐Ming Zhang, Yun Luo, Rong‐Huan Zhong, Zhong‐Guo Zhou, Yan‐Jun Xu, Xiao‐Jun Xu, Wen‐Hua Ling, Min‐Shan Chen, Hui‐Lian Zhu – 2 November 2019