Is Portal Inflow Modulation Always Necessary for Successful Utilization of Small Volume Living Donor Liver Grafts?

Arvinder Singh Soin, Sanjay Kumar Yadav, Sujeet Kumar Saha, Amit Rastogi, Prashant Bhangui, Thiagarajan Srinivasan, Neeraj Saraf, Narendra S. Choudhary, Sanjeev Saigal, Vijay Vohra – 22 August 2019 – Although the well‐accepted lower limit of the graft‐to‐recipient weight ratio (GRWR) for successful living donor liver transplantation (LDLT) remains 0.80%, many believe grafts with lower GRWR may suffice with portal inflow modulation (PIM), resulting in equally good recipient outcomes. This study was done to evaluate the outcomes of LDLT with small‐for‐size grafts (GRWR <0.80%).

Hepatic Encephalopathy Is Reversible in the Long Term After Liver Transplantation

Anna‐Elisabeth Hopp, Meike Dirks, Carlotta Petrusch, Annemarie Goldbecker, Anita Blanka Tryc, Hannelore Barg‐Hock, Christian Strassburg, Jürgen Klempnauer, Karin Weissenborn, Henning Pflugrad – 22 August 2019 – Cognitive dysfunction caused by hepatic encephalopathy (HE) improves within the first year after liver transplantation (LT). However, cognitive restitution seems to be incomplete in a subset of patients and after LT a new‐onset cognitive decline was described. Data about the longterm development of cognitive function after liver transplantation (LT) are sparse.

Development of a Model to Predict Portal Vein Thrombosis in Liver Transplant Candidates: The Portal Vein Thrombosis Risk Index

Daniel Gaballa, Dmitri Bezinover, Zakiyah Kadry, Elaine Eyster, Ming Wang, Patrick G. Northup, Jonathan G. Stine – 22 August 2019 – Portal vein thrombosis (PVT) is associated with inferior pretransplantation and posttransplantation outcomes. We aimed to create a predictive model to risk stratify transplant candidates for PVT. Data on adult transplants in the United States during the Model for End‐Stage Liver Disease (MELD) era through September 2016 were reviewed.

Impact of Hepatic Steatosis on Resting Metabolic Rate and Metabolic Adaptation in Response to Intentional Weight Loss

Vikrant P. Rachakonda, James P. DeLany, Erin E. Kershaw, Jaideep Behari – 21 August 2019 – Weight loss is the primary intervention for nonalcoholic fatty liver disease (NAFLD). A decrease in resting metabolic rate (RMR) out of proportion to the degree of weight loss may promote weight regain. We aimed to determine the impact of hepatic steatosis on weight loss‐associated changes in RMR and metabolic adaptation, defined as the difference between predicted and measured RMR after weight loss.

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