A Tribute to AASLD Member Shreya Sengupta, MD

With sadness, AASLD acknowledges the passing of Shreya “Mou” Sengupta, MD. Dr. Sengupta was a gifted clinician, rising health services researcher, and fierce advocate for the most vulnerable. She passed away peacefully at home on July 28, 2025, at the age of 40, surrounded by her loving family after a courageous battle with pancreatic cancer. Dr. Sengupta’s compassion and unwavering commitment to others made her a beloved presence in her personal and professional circles. Her loss is deeply felt across the hepatology community.

“Shreya was a light in our everyday work radiating warmth, positivity, and inspiration to everyone around her.” – Dr. Jamak Modaresi

Born in Ranchi, India, Dr. Sengupta earned her medical degree from the University of Illinois at Chicago and completed her Med-Peds residency at the University of Chicago in 2015. She then pursued fellowships in gastroenterology and transplant hepatology at the University of Michigan, where she developed a lifelong commitment to equity and integrated care. Following her training, Dr. Sengupta joined the Cleveland Clinic, where she spent her entire faculty career. She served as Quality Improvement Officer for the Section of Hepatology and as Director of the Multidisciplinary Alcohol Program, one of the nation’s one of the first clinics offering longitudinal, team-based care for patients with alcohol-associated liver disease (ALD) and alcohol use disorder. This innovative model, which brought together hepatology, addiction psychiatry and social work, redefined care for a historically stigmatized and underserved population. Her work became a national blueprint for equitable, multidisciplinary care in hepatology.

“Mou is one of those fellows/colleagues that you will never forget —always looking out for those who need help most. This led to her establishing a multi-disciplinary clinic for patients with alcohol-associated liver disease, the most vulnerable in our hepatology practice. The hepatology community lost a bright star.” – Dr. Anna Lok

Dr. Sengupta leaves a legacy of advancing the science and delivery of care in ALD. She was a serving member of the AASLD Public Policy Committee and Alcohol-associated Liver Disease Special Interest Group (SIG). Through her work, she actively shaped national strategies to combat liver disease, promote health equity, and support underserved communities.

Her research focused on ALD, public health, and health equity. In one pivotal study, she demonstrated that integrated multidisciplinary care significantly reduced hepatic decompensation, hospitalizations, and alcohol use among patients with advanced ALD. In a separate national analysis, she published data revealing rising emergency visits and hospitalizations for  younger adult with ALD, highlighting the growing severity and healthcare burden of this condition. Her international work included a time-series analysis examining racial disparities in ALD hospitalizations in Brazil during the COVID-19 pandemic. Additionally, in a widely cited narrative review, she explored the connection between alcohol policy and liver outcomes, advocating for effective, population-level interventions. Through her editorial writing, Dr. Sengupta challenged traditional abstinence-based measures of post-transplant success. She called for more compassionate approaches that integrate harm reduction, mental health, and patient-centered outcomes. Her work was consistently grounded in scientific rigor and moral clarity, always emphasizing how healthcare systems could better serve high-risk populations. 

“Mou’s work on integrative care in ALD was the model everyone should follow. She was a real leader.” – Dr. Elliot Tapper

Dr. Sengupta was also a dedicated educator and mentor, closely guiding students, fellows, junior faculty, and advanced practice providers. As a mentor within the AASLD Emerging Liver Advanced Practice Provider Program, she inspired many who now carry forward her legacy.

“...We will all miss her honesty, integrity, and forthright nature in caring for patients and sharing her passions and perspectives on life with others.” – Dr. Robert Fontana

Amidst her extraordinary professional achievements, Dr. Sengupta’s greatest joy and purpose came from being a mother to her beloved sons, Sohum and Satya, and a partner to her devoted husband, Baylee Miller. 

Dr. Sengupta committed herself fully to science, equity, and those she loved. We honor her by carrying forward the mission she held dear: to lead with integrity, lift others, and care deeply—for our patients, our colleagues, and our communities. 

To make a donation to AASLD Foundation in Dr. Shreya (Mou) Sengupta’s memory, please click here.

Written by:
Sobia Laique, MD
Akhil Anand, MD
Pratima Sharma, MD
Jessica Mellinger, MD
Monica Tincopa, MD