Michael A Heneghan

Professor Michael Heneghan is a Consultant Hepatologist & Professor of Hepatology at King's College Hospital London for over 20 years. His principal interests are in the field of liver transplantation, autoimmune liver disease and pregnancy associated liver disease. He has published more than 250 original articles and papers in peer-reviewed journals. He has served as Secretary of the British Association for the Study of the Liver.

Binita M Kamath

Binita was educated at Cambridge University and trained at several London hospitals, including Kings College Hospital. She moved to the Children's Hospital of Philadelphia in 2000 and completed her fellowship in GI, Hepatology and Nutrition. She joined the faculty in 2006 and developed a strong interest in cholestatic liver disease, specifically Alagille syndrome. She joined the faculty at the Hospital for Sick Children, Toronto in 2009 as a Hepatologist and Clinician-Investigator continuing to work on biliary diseases and utilizing stem cell biology to develop disease models.

Rethinking MASH: Integrating Systemic Risk with Liver-Centered Disease Mechanisms

MASLD arises within systemic metabolic dysfunction, but what determines progression to MASH and fibrosis within the liver? This program examines how hepatic metabolic adaptation can become maladaptive under persistent stress, triggering cellular injury, inflammatory signaling, and fibrogenesis that drive progressive liver disease.

Industry Supporter: Madrigal Pharmaceuticals Inc.

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