Kupffer cell and interleukin‐12–dependent loss of natural killer T cells in hepatosteatosis

Michael Kremer, Emmanuel Thomas, Richard J. Milton, Ashley W. Perry, Nico van Rooijen, Michael D. Wheeler, Steven Zacks, Michael Fried, Richard A. Rippe, Ian N. Hines – 23 December 2009 – Hepatosteatosis is associated with increased expression of tumor necrosis factor alpha (TNF‐α) and interleukin (IL)‐12, major T helper (Th) 1 cytokines, and reduced hepatic natural killer T (NKT) cell numbers. The relationship between lipid accumulation, cytokine expression, and hepatic NKT cells is not known.

Alcoholic liver disease

Robert S. O'Shea, Srinivasan Dasarathy, Arthur J. McCullough, Practice Guideline Committee of the American Association for the Study of Liver Diseases and the Practice Parameters Committee of the American College of Gastroenterology – 23 December 2009

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