Living donor liver transplantation for hepatitis C‐related cirrhosis: No difference in histological recurrence when compared to deceased donor liver transplantation recipients

Linsheng Guo, Mauricio Orrego, Hector Rodriguez‐Luna, Vijiyan Balan, Thomas Byrne, Kapil Chopra, David D. Douglas, Edwyn Harrison, Adyr Moss, K. Sudhakar Reddy, James W. Williams, Jorge Rakela, David Mulligan, Hugo E. Vargas – 22 March 2006 – The question of possible earlier and more aggressive recurrence of hepatitis C virus (HCV) infection after living donor liver transplantation (LDLT) compared to deceased donor liver transplantation (DDLT) remains unanswered.

Nonalcoholic fatty liver disease and liver transplantation

Paul Angulo – 22 March 2006 – Nonalcoholic fatty liver disease affects a substantial proportion of the general population worldwide. This high prevalence of nonalcoholic fatty liver disease has important consequences in the donor selection process for liver transplantation, and in the posttransplant period given the high recurrence rate of disease. This paper reviews the prevalence of nonalcoholic fatty liver disease, its progressive potential, and the implications of this liver condition in both the pre‐ and post‐liver transplantation setting. Liver Transpl 12:523–534, 2006.

Fever, mental impairment, acute anemia, and renal failure in patient undergoing orthotopic liver transplantation: Posttransplantation malaria

Francesco Menichetti, Maria Lucia Bindi, Carlo Tascini, Lucio Urbani, Gianni Biancofiore, Roberta Doria, Massimo Esposito, Roberto Mozzo, Gabriele Catalano, Franco Filipponi – 22 March 2006 – A case of post‐transplant malaria is described. The patient presented fever and severe anemia after orthotopic liver transplantation. Diagnosis was made only after the review of donor characteristics. Although a high parasitemia was found at the moment of diagnosis, the treatment with quinine and doxycycline was successful.

KICG value, a reliable real‐time estimator of graft function, accurately predicts outcomes in adult living‐donor liver transplantation

Tomohide Hori, Taku Iida, Shintaro Yagi, Kentaro Taniguchi, Chiduru Yamamoto, Shugo Mizuno, Kentaro Yamagiwa, Shuji Isaji, Shinji Uemoto – 22 March 2006 – Reliable monitoring enabling evaluation of graft function is crucial after living‐donor liver transplantation (LDLT). A method to identify poor graft function at an early postoperative period would allow opportune intensive clinical management to bring about further improvements in LDLT outcomes.

Gene array analysis of a rat model of liver transplant tolerance identifies increased complement C3 and the STAT‐1/IRF‐1 pathway during tolerance induction

Shaun P. Cordoba, Chuanmin Wang, Rohan Williams, Jian Li, Lynn Smit, Alexandra Sharland, Richard Allen, Geoffrey McCaughan, Alex Bishop – 22 March 2006 – This study aimed to define the molecular mechanism during induction of spontaneous liver transplant tolerance using microarrays and to focus on molecular pathways associated with tolerance by meta‐analysis with published studies. The differences in the early immune response between PVG to DA liver transplant recipients that are spontaneously tolerant (TOL) and PVG to Lewis liver transplants that reject (REJ) were examined.

Subscribe to