Montserrat Ferrer, Juan Córdoba, Olatz Garin, Gemma Olivé, Montserrat Flavià, Victor Vargas, Rafael Esteban, Jordi Alonso – 28 December 2005 – The Chronic Liver Disease Questionnaire (CLDQ) measures the impact on quality of life of chronic liver diseases, regardless of underlying etiology. The aim of this study was to develop a Spanish version of the CLDQ, and to assess its acceptability, reliability, validity, and sensitivity to change. The forward and back‐translation method by bilingual translators, with expert panel and pilot testing on patients, was used for the adaptation.

Benjamin L. Shneider, Frederick J. Suchy, Sukru Emre – 28 December 2005 – Since February 2002, the Pediatric End Stage Liver Disease (PELD) scoring system has been utilized as a means of prioritizing children for liver transplantation. The United Network for Organ Sharing database was queried to assess utilization of PELD in 2003 and 2004; 682 liver transplants were performed in pediatric recipients where the PELD score was potentially the primary determinant of liver allocation.

Michael A. Silva, Periyathambi S. Jambulingam, Bridget K. Gunson, David Mayer, John A.C. Buckels, Darius F. Mirza, Simon R. Bramhall – 28 December 2005 – Hepatic artery thrombosis (HAT) occurs in 3–9% of all liver transplants and acute graft loss is a possible sequelae. We present our experience in the management of HAT over a 10‐year period. Prospectively collected data from April 1994 to April 2004 were analyzed. There were 1,257 liver transplants, 669 males, median age 51 (16–73) years. There were 61 (4.9%) cases of HAT. Early HAT occurred in 21 (1.8%).

Claire Terry, Anil Dhawan, Ragai R. Mitry, Sharon C. Lehec, Robin D. Hughes – 28 December 2005 – Cryopreservation of human hepatocytes is important for the treatment of liver disease by hepatocyte transplantation and also for the use of hepatocytes as an in vitro model of the liver. One factor in the success of cryopreservation is the quality of cells before freezing.

Janis E. Blair – 28 December 2005 – Coccidioidomycosis is an endemic fungal infection in the southwestern United States. It causes morbidity and mortality among solid organ transplant recipients who reside in or visit the endemic area or who receive organs from donors infected with the fungus. This paper reviews current literature addressing these infections in liver transplantation programs, including risk factors, clinical manifestations in persons with cirrhosis or who have had a liver transplantation, prophylaxis, treatment, and outcomes. Liver Transpl 12:31–39, 2006. © 2005 AASLD.

Gary L. Davis – 28 December 2005

Shin Hwang, Sung‐Gyu Lee, Chul‐Soo Ahn, Deok‐Bog Moon, Ki‐Hun Kim, Tae‐Yong Ha, Gi‐Won Song – 28 December 2005

Kazushige Sato, Satoshi Sekiguchi, Yorihiro Akamatsu, Naoki Kawagishi, Yoshitaka Enomoto, Takeru Iwane, Akira Sato, Keisei Fujimori, Susumu Satomi – 28 December 2005 – Hemorrhagic complications commonly occur early after liver transplantation (LT), sometimes requiring emergent relaparotomy. However, active bleeding from the liver graft itself is a rare but life‐threatening complication after living donor liver transplantation (LDLT).

Shikha S. Sundaram, Hector Melin‐Aldana, Katie Neighbors, Estella M. Alonso – 28 December 2005 – Cellular rejection is a common event in orthotopic liver transplantation, leading to significant morbidity and mortality. Late acute cellular rejection, which occurs at least 3 months post‐transplant, affects 8–32% of pediatric liver transplant recipients. The histopathology and clinical outcome of patients affected by late cellular rejection are incompletely understood.

Philippa F. Middleton, Michael Duffield, Stephen V. Lynch, Robert T.A. Padbury, Tony House, Peter Stanton, Deborah Verran, Guy Maddern – 28 December 2005 – The objective of this study was to evaluate the safety and efficacy of adult‐to‐adult living donor liver transplantation, specifically donor outcomes. A systematic review, with searches of the literature up to January 2004, was undertaken. Two hundred and fourteen studies provided information on donor outcomes.