Ribavirin mutagenesis: Hidden clues in mathematical models
Zhi Hong – 24 May 2005
Fulminant hepatic failure
David A. Sass, A. Obaid Shakil – 24 May 2005
Transmission of an undiagnosed sarcoma to recipients of kidney and liver grafts procured in a non‐heart beating donor
Olivier Detry, Arnaud De Roover, Laurence de Leval, Christian Herens, Jean Delwaide, Pierre Honoré, Michel Meurisse – 24 May 2005 – Transmission of an undiagnosed cancer with solid organ transplantation is a rare but dreadful event. In this paper the authors report the transmission of an undiagnosed sarcoma to recipients of kidney and liver grafts procured in a Maastricht category 3 non‐heart beating donor. To the authors' knowledge this case is the first report of such a transmission with a liver graft procured in a non‐heart beating donor.
Progress toward the therapy of hepatitis with RNAi
Glenn Rendall – 24 May 2005
Adjuvant iodine‐131‐labeled lipiodol for prevention of intrahepatic recurrence of hepatocellular carcinoma: Which is the best treatment schedule?
Marco Tabone, Luca Vigano, Cristiana Laudi, Alessandro Ferrero, Riccardo Pellerito, Lorenzo Capussotti – 23 May 2005
Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication
David V. Morrissey, Karin Blanchard, Lucinda Shaw, Kristi Jensen, Jennifer A. Lockridge, Brent Dickinson, James A. McSwiggen, Chandra Vargeese, Keith Bowman, Chris S. Shaffer, Barry A. Polisky, Shawn Zinnen – 23 May 2005 – To develop synthetic short interfering RNA (siRNA) molecules as therapeutic agents for systemic administration in vivo, chemical modifications were introduced into siRNAs targeted to conserved sites in hepatitis B virus (HBV) RNA. These modifications conferred significantly prolonged stability in human serum compared with unmodified siRNAs.
AASLD practice guidelines: Evaluation of the patient for liver transplantation
Karen F. Murray, Robert L. Carithers – 23 May 2005
Changes in gallbladder bile composition and crystal detection time in morbidly obese subjects after bariatric surgery
Ulf Gustafsson, Lisbet Benthin, Lars Granström, Albert K. Groen, Staffan Sahlin, Curt Einarsson – 23 May 2005 – The aim of the present study was to elucidate the mechanisms of development of cholesterol crystals and gallstones during weight reduction in obese subjects. Twenty‐five morbidly obese, gallstone‐free subjects underwent vertical‐banded gastroplasty. Gallbladder bile was collected at the time of the operation via needle aspiration and 1.1–7.3 months after the operation via ultrasound‐guided transhepatic puncture of the gallbladder. The mean weight loss was 17 kg.
A novel 3D hepatectomy simulation based on liver circulation: Application to liver resection and transplantation
Shinichi Saito, Junichi Yamanaka, Koui Miura, Norio Nakao, Tomohiro Nagao, Takaaki Sugimoto, Tadamichi Hirano, Nobukazu Kuroda, Yuji Iimuro, Jiro Fujimoto – 23 May 2005 – Hepatectomy is a complicated operative procedure because of its anatomical complexity, vascular variability, and impaired hepatic function due to associated hepatitis or cirrhosis. Thus preoperative detailed topography and precise liver resection volume measurements should be obtained for a curative hepatectomy.