Javier Crespo, Monteserrat Rivero, Marta Mayorga, Emilio Fabrega, Fernando Casafont, Manuel Gomez‐Fleitas, Fernando Pons‐Romero – 30 December 2003 – To date, there have been no reports of the involvement of the Fas system in recurrent hepatitis C virus (HCV) infection after orthotopic liver transplantation (OLT). In 25 patients who underwent OLT for HCV‐related liver cirrhosis, we evaluated the expression of the Fas antigen (FasAg) on hepatocytes, apoptic hepatocytes, and serum levels of soluble Fas (sFas).

Pedro W. Baron, David Sindram, Dave Higdon, David N. Howell, Marcia R. Gottfried, Janet E. Tuttle‐Newhall, Pierre‐Alain Clavien – 30 December 2003 – The majority of patients undergoing orthotopic liver transplantation (OLT) have end‐stage liver disease secondary to hepatitis C virus (HCV) infection. Although OLT does not cure the disease and recurrent virus is present in all patients, relatively few patients with recurrent viremia develop clinical disease. When the disease recurs, however, the results can be devastating.

Christopher P. Snowden, Tracey Hughes, John Rose, David R.D. Roberts – 30 December 2003 – The aim of this study is to determine the incidence of radiological pulmonary edema in elective liver transplant recipients and its relationship to perioperative factors and postoperative course. We reviewed 102 chest radiographs from 34 patients who had undergone orthotopic liver transplantation (OLT). Films were assessed by 2 trained radiologists for evidence of pulmonary edema using a standardized system. Clinical and outcome data from the 34 patients were also recorded.

Jan Stange, Steffen R. Mitzner, Sebastian Klammt, Jens Freytag, Piotr Peszynski, Jan Loock, Heiko Hickstein, Gero Korten, Reinhardt Schmidt, Jörg Hentschel, Martin Schulz, Matthias Löhr, Stefan Liebe, Wolfgang Schareck, Ullrich T. Hopt – 30 December 2003 – Liver failure associated with excretory insufficiency and jaundice results in an endogenous accumulation of toxins involved in the impairment of cardiovascular, kidney, and cerebral function.

J. Ignacio Herrero, Jorge Quiroga, Bruno Sangro, Oscar Beloqui, Fernando Pardo, Javier A. Cienfuegos, Jesús Prieto – 30 December 2003 – Liver transplant recipients have an increased risk for cardiovascular disease because of a high incidence of obesity, arterial hypertension, diabetes mellitus, and hyperlipidemia. Hyperhomocysteinemia has been found to be an important risk factor for cardiovascular disease in large studies.

Kenneth E. Drazan – 30 December 2003

Stephen P. Pereira, Louise M. Howard, Paolo Muiesan, Mohammed Rela, Nigel Heaton, Roger Williams – 30 December 2003 – There are few data on predictive factors for alcohol relapse or long‐term functional outcome after liver transplantation for alcoholic liver disease (ALD).

Robyn S. Shapiro, Mark Adams – 30 December 2003 – Key Points

Amadeo Marcos – 30 December 2003 – Key Points

Vincent T. Armenti, Steven K. Herrine, John S. Radomski, Michael J. Moritz – 30 December 2003 – The first known posttransplantation pregnancy was in 1958 in a renal transplant recipient who had received a kidney from her identical twin sister. The first known posttransplantation pregnancy in a liver transplant recipient was in 1978. Information available from female kidney transplant recipients helped in the decision making involved in the management of this case, as well as those that followed.