Hepatitis B e antigen–negative chronic hepatitis b in Hong Kong

Henry L. Y. Chan, Nancy W. Y. Leung, Munira Hussain, May L. Wong, Anna S. F. Lok – 30 December 2003 – Hepatitis B e antigen–negative chronic hepatitis B (e−CHB) has been reported in Asia but its prevalence and clinical significance have not been determined. The aims of this study were to determine the prevalence of e−CHB in Hong Kong and the frequency of precore and core promoter mutations in these patients. A cross‐sectional study was performed in 350 consecutive Chinese patients (230 men and 120 women; mean age ±SD, 42 ± 13 years) with chronic hepatitis B virus infection.

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