Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats fed diets high in corn oil and fish oil
Rathnagiri Polavarapu, Douglas R. Spitz, Julia E. Sim, Mark H. Follansbee, Larry W. Oberley, Amir Rahemtulla, Amin A. Nanji – 30 December 2003 – Increased hepatic oxidative stress with ethanol administration is hypothesized to be caused either by enhanced pro‐oxidant production or decreased levels of antioxidants or both. We used the intragastric feeding rat model to assess the relationship between hepatic antioxidant enzymes and pathological liver injury in animals fed different dietary fats.