Development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B
Chung‐Mau Lo, James Tak‐Kwan Fung, George Ka‐Kit Lau, Chi‐Leung Liu, Siu‐Tim Cheung, Ching‐Lung Lai, Sheung‐Tat Fan, John Wong – 30 December 2003 – Patients with chronic hepatitis B virus (HBV) infection have a defective HBV‐specific immune response, and the spontaneous development of antibody against hepatitis B surface antigen (anti‐HBs) after liver transplantation has not been observed. We report the spontaneous production of anti‐HBs in 21 of 50 (42%) patients receiving lamivudine monoprophylaxis after liver transplantation.