Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids

Mikel Ruiz de Gauna, Francesca Biancaniello, Francisco González‐Romero, Pedro M. Rodrigues, Ainhoa Lapitz, Beatriz Gómez‐Santos, Paula Olaizola, Sabina Di Matteo, Igor Aurrekoetxea, Ibone Labiano, Ane Nieva‐Zuluaga, Asier Benito‐Vicente, María J. Perugorria, Maider Apodaka‐Biguri, Nuno A. Paiva, Diego Sáenz de Urturi, Xabier Buqué, Igotz Delgado, César Martín, Mikel Azkargorta, Felix Elortza, Diego F. Calvisi, Jesper B. Andersen, Domenico Alvaro, Vincenzo Cardinale, Luis Bujanda, Jesús M. Banales, Patricia Aspichueta – 13 January 2022

Graft Fibrosis Over 10 to 15 Years in Pediatric Liver Transplant Recipients: Multicenter Study of Paired, Longitudinal Surveillance Biopsies

Emily R. Perito, Elodie Persyn, John Bucuvalas, Mercedes Martinez, Saeed Mohammad, James E. Squires, Anthony J. Demetris, Sandy Feng – 12 January 2022 – Previous single‐center, cross‐sectional studies have reported a steep increase in the prevalence and severity of fibrosis through 10 to 15 years after pediatric liver transplantation. We report a multicenter study of paired surveillance biopsies in a contemporary cohort.

The digital transformation of hepatology: The patient is logged in

Tiffany Wu, Douglas A. Simonetto, John D. Halamka, Vijay H. Shah – 12 January 2022 – The rise in innovative digital health technologies has led a paradigm shift in health care toward personalized, patient‐centric medicine that is reaching beyond traditional brick‐and‐mortar facilities into patients’ homes and everyday lives. Digital solutions can monitor and detect early changes in physiological data, predict disease progression and health‐related outcomes based on individual risk factors, and manage disease intervention with a range of accessible telemedicine and mobile health options.

T cells: Friends and foes in NASH pathogenesis and hepatocarcinogenesis

Pierluigi Ramadori, Shing Kam, Mathias Heikenwalder – 11 January 2022 – In association with the pandemic spreading of obesity and metabolic syndrome, the prevalence of NAFLD‐related HCC is increasing almost exponentially. In recent years, many of the underlining multifactorial causes of NAFLD have been identified, and the cellular mechanisms sustaining disease development have been dissected up to the single‐cell level.

Risk Factors for Posttransplantation Mortality in Recipients With Grade 3 Acute‐on‐Chronic Liver Failure: Analysis of a North American Consortium

Vinay Sundaram, Sarvanand Patel, Kirti Shetty, Christina C. Lindenmeyer, Robert S. Rahimi, Gianina Flocco, Atef Al‐Attar, Constantine J. Karvellas, Suryanarayana Challa, Harapriya Maddur, Janice H. Jou, Michael Kriss, Lance L. Stein, Alex H. Xiao, Ross H. Vyhmeister, Ellen W. Green, Braidie Campbell, William Cranford, Nadim Mahmud, Brett E.

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