Caution Regarding Endoscopic Balloon Placement and the Risk of Sarcopenia in Liver Transplant Candidates
Penelope Hey, Jonathan Ng, Marie Sinclair – 8 January 2022
NOD‐like receptor protein 3 activation causes spontaneous inflammation and fibrosis that mimics human NASH
David M. Calcagno, Angela Chu, Susanne Gaul, Nika Taghdiri, Avinash Toomu, Aleksandra Leszczynska, Benedikt Kaufmann, Bettina Papouchado, Alexander Wree, Lukas Geisler, Hal M. Hoffman, Ariel E. Feldstein, Kevin R. King – 7 January 2022
TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara – 6 January 2022
The rise and fall and rise again of ammonia as a therapeutic target in HE
Thomas H. Tranah, Debbie L. Shawcross – 6 January 2022
Hepatic interferon regulatory factor 8 expression suppresses hepatocellular carcinoma progression and enhances the response to anti–programmed cell death protein‐1 therapy
Hongxi Wu, Yan Li, Guangjiang Shi, Shijia Du, Xiaobin Wang, Wanli Ye, Zixuan Zhang, Ya Chu, Shuqian Ma, Dajia Wang, Yuan Li, Zhen Chen, Lutz Birnbaumer, Zhuo Wang, Yong Yang – 5 January 2022
Noninvasive Prediction of Outcomes in Autoimmune Hepatitis–Related Cirrhosis
Laura‐Patricia Llovet, Jordi Gratacós‐Ginès, Luis Téllez, Ana Gómez‐Outomuro, Carmen A. Navascués, Mar Riveiro‐Barciela, Raquel Vinuesa, Judith Gómez‐Camarero, Montserrat García‐Retortillo, Fernando Díaz‐Fontenla, Magdalena Salcedo, María García‐Eliz, Diana Horta, Marta Guerrero, Manuel Rodríguez‐Perálvarez, Conrado Fernández‐Rodriguez, Agustín Albillos, Juan G‐Abraldes, Albert Parés, Maria‐Carlota Londoño – 5 January 2022 – The value of noninvasive tools in the diagnosis of autoimmune hepatitis (AIH)–related cirrhosis and the prediction of clinical outcomes is largely unknown.
Digitizing DILI: Who can? RUCAM? RECAM?
James H. Lewis – 5 January 2022
Surgical Outcomes of Domino Liver Transplantation Using Grafts From Living Donors With Familial Amyloid Polyneuropathy
Hidekazu Yamamoto, Yuzuru Sambommatsu, Masatsugu Ishii, Keita Shimata, Kaori Isono, Masaki Honda, Yasuhiko Sugawara, Yukihiro Inomata, Taizo Hibi – 5 January 2022 – Domino liver transplantation (DLT) using grafts from donors with familial amyloid polyneuropathy is an acceptable procedure for expanding the donor pool. The vascular and biliary reconstructions in living donor DLT (LDDLT) are technically demanding, and data on the short‐term and long‐term surgical outcomes of domino donors and recipients in LDDLT are limited.
Getting to HBV cure: The promising paths forward
Scott Fung, Hannah S. J. Choi, Adam Gehring, Harry L. A. Janssen – 5 January 2022 – Chronic HBV infection is a global public health burden estimated to impact nearly 300 million persons worldwide. Despite the advent of potent antiviral agents that effectively suppress viral replication, HBV cure remains difficult to achieve because of the persistence of covalently closed circular DNA (cccDNA), HBV‐DNA integration into the host genome, and impaired immune response. Indefinite treatment is necessary for most patients to maintain level of viral suppression.