Ljudevit L. Andres, Vinod K. Sawhney, George H. Scullard, Joseph L. Smith, Thomas C. Merigan, William S. Robinson, Peter B. Gregory – 1 November 1981 – Fifty patients with chronic HBs antigenemia and Dane particle‐associated DNA polymerase and HBeAg in their serum were contrasted to 46 HBsAg positive patients who had neither serum DNA polymerase or HBeAg. The time from acute onset and the duration of antigenemia were longer in patients who were DNA polymerase and HBeAg negative than in those who had both serum markers.

Harold O. Conn – 1 November 1981

Dean J. Tuma, Richard B. Jennett, Michael F. Sorrell – 1 November 1981 – The effects of ethanol on the synthesis and secretion of serum glycoproteins and albumin, a nonglycosylated protein, were studied in rat liver slices. Serum glycoproteins and albumin were determined by immunoprecipitation from either the incubation medium or from the washed slices. When ethanol (10 mM) was present in the incubation medium, [14C]glucosamine incorporation in secretory glycoproteins was decreased.

Sugantha Govindarajan, Mary Ashcavai, Robert L. Peters – 1 November 1981 – α‐1‐Antitrypsin deficiency due to homozygous Pi ZZ state is reported to be associated with cirrhosis and hepatocellular carcinoma (HCC); however, the role of heterozygous Pi Z state is not definitively known. In order to investigate the possible association, we studied the phenotypic distribution of α‐1‐antitrypsin variants (Pi) in 124 cases of HCC. Two thousand ten normal American Red Cross blood donors were studied as controls.

Jurgen Ludwig, Steven S. Barham, Nicholas F. Larusso, Lila R. Elveback, Russell H. Wiesner, John T. McCall – 1 November 1981 – Histologic, ultrastructural, chemical, and statistical methods were used to study liver biopsy and autopsy specimens from 43 patients who had primary sclerosing cholangitis (PSC), with or without chronic ulcerative colitis (CUC), and from 19 patients who had CUC without PSC. In all study groups, essentially the same abnormalities were found in the hepatic parenchyma outside the major bile ducts, although nondiagnostic tissue samples were observed also.

Charles S. Davidson – 1 November 1981

Michael A. Dunn, Refaat Kamel – 1 November 1981

1 September 1981

Ferruccio Bonino, Bill Hoyer, Judith Nelson, Ronald Engle, Giorgio Verme, John Gerin – 1 September 1981 – Sera and liver biopsies from 30 Italian patients, carriers of HBsAg for at least 3 years, were examined for markers of hepatitis B virus (HBV) infection by serological assays and immunofluorescence. Biopsies were analyzed for HBcAg, HBsAg, and δ antigen by immunofluorescence; sera were assayed for HBsAg/anti‐HBs, HBcAg/anti‐HBc, HBeAg/anti‐HBe, δ/anti‐δ, HBV‐specific DNA polymerase activity and the presence of HBV DNA.

Douglas R. LaBrecque, Arun K. Dhand – 1 September 1981 – The staff and patients in hemodialysis units have the greatest hospital risk of acquiring hepatitis B (HB) infection. We followed the patients of two dialysis nurses in two different dialysis units. One nurse dialyzed 19 patients a total of 50 times during the prodrome of acute HB. The second nurse was a known, asymptomatic carrier of HBsAg who was also HBeAg(+) and anti‐HBc(+). Over a 2‐year period, she dialyzed 30 patients a total of 742 times.