Liver Transplantation for Acute Liver Injury in Asians Is More Likely Due to Herbal and Dietary Supplements

Varun Kesar, Lindsey Channen, Umair Masood, Priya Grewal, Jawad Ahmad, Nitzan C. Roth, Joseph A. Odin – 8 August 2021 – Drug‐induced liver injury (DILI) due to medications and herbal and dietary supplements (HDSs) is a major cause of acute liver injury leading to liver transplantation (LT). This study used United Network for Organ Sharing LT data to analyze severe HDS‐induced acute liver injury in the United States.

Anticancer Effect of Statins in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma

Hae Lim Lee, Sung Won Lee, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Ho Joong Choi, Gun Hyung Na, Young Kyoung You, Il Young Park, Dong Goo Kim – 8 August 2021 – The anticancer effect of statins is drawing attention. However, it is unclear whether statin use reduces the risk of hepatocellular carcinoma (HCC) recurrence in patients who undergo liver transplantation (LT) for HCC. Consecutive patients who underwent LT for HCC between 1995 and 2019 were enrolled.

Center Variability in Acute Rejection and Biliary Complications After Pediatric Liver Transplantation

Mounika Kanneganti, Yuwen Xu, Yuan‐Shung Huang, Eimear Kitt, Brian T. Fisher, Peter L. Abt, Elizabeth B. Rand, Douglas E. Schaubel, Therese Bittermann – 7 August 2021 – Transplant center performance and practice variation for pediatric post–liver transplantation (LT) outcomes other than survival are understudied. This was a retrospective cohort study of pediatric LT recipients who received transplants between January 1, 2006, and May 31, 2017, using United Network for Organ Sharing (UNOS) data that were merged with the Pediatric Health Information System database.

Deceased Donor Liver Transplantation After Radioembolization for Hepatocellular Carcinoma and Portal Vein Tumoral Thrombosis: A Pilot Study

Matteo Serenari, Alberta Cappelli, Alessandro Cucchetti, Cristina Mosconi, Lidia Strigari, Fabio Monari, Matteo Ravaioli, Elisa Lodi Rizzini, Stefano Fanti, Rita Golfieri, Matteo Cescon – 5 August 2021 – Hepatocellular carcinoma (HCC) with portal vein tumoral thrombosis (PVTT) represents a major concern especially in the field of deceased donor liver transplantation (DDLT). However, when receiving transarterial radioembolization (TARE), a considerable percentage of such patients are able to achieve a radiologic complete response with adequate survival rates.

Prospective Study of Withdrawal of Antiviral Therapy in Patients with Chronic Hepatitis B after Prolonged Virological Response

Naveen Gara, Michele M. Tana, Meera Kattapuram, Sungyoung Auh, Lauren Sullivan, Nancy Fryzek, Mary Walter, Regina Umarova, Xiongce Zhao, Gavin Cloherty, Edward Doo, Theo Heller, T. Jake Liang, Marc G. Ghany – 5 August 2021 – Nucleoside analogue (NA) therapy for chronic hepatitis B (CHB) is associated with improved clinical outcomes, but usually requires long‐term use. Whether treatment can be safely withdrawn and the factors associated with post‐withdrawal outcome are not well defined.

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