Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults: Systematic Review and Meta‐Analysis

Steven Young, Raseen Tariq, John Provenza, Sanjaya K. Satapathy, Kamal Faisal, Abhijit Choudhry, Scott L. Friedman, Ashwani K. Singal – 21 May 2020 – Data on prevalence and profile of nonalcoholic fatty liver disease (NAFLD) among individuals who are lean (normal body mass index) is unclear. Published data from studies comparing lean with obese NAFLD or with healthy subjects on prevalence, comorbidities, liver chemistry and histology, and metabolic/inflammatory markers were analyzed.

Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis

Olga Protchenko, Ethan Baratz, Shyamalagauri Jadhav, Fengmin Li, Minoo Shakoury‐Elizeh, Oksana Gavrilova, Manik C. Ghosh, James E. Cox, J. Alan Maschek, Vladimir A. Tyurin, Yulia Y. Tyurina, Hülya Bayir, Allegra T. Aron, Christopher J. Chang, Valerian E. Kagan, Caroline C. Philpott – 21 May 2020

Surgical Treatments of Hepatobiliary Cancers

Ganesh Gunasekaran, Yuki Bekki, Vennis Lourdusamy, Myron Schwartz – 21 May 2020 – Hepatobiliary cancers which include hepatocellular carcinoma (HCC) and biliary tract cancers (i.e., cholangiocarcinoma and gallbladder carcinoma) are associated with significant morbidity and mortality based on the stage of the disease at presentation. With improved screening for hepatobiliary malignancies in patients with risk factors and with widespread use of laparoscopic cholecystectomy, hepatobiliary malignancies, including incidental diagnosis of gallbladder carcinoma, are on the rise.

Use of Skeletal Muscle Index as a Predictor of Wait‐List Mortality in Patients With End‐Stage Liver Disease

Matthew R. Kappus, Kara Wegermann, Erol Bozdogan, Yuval A. Patel, Gemini Janas, Erin Shropshire, Alice Parish, Donna Niedzwiecki, Andrew J. Muir, Mustafa Bashir – 20 May 2020 – The aim of this study is to validate a proposed definition of sarcopenia in predicting wait‐list mortality. We retrospectively evaluated 355 adults (age ≥18 years) with cirrhosis listed for first‐time LT from January 1, 2010, to April 1, 2018 from our center. Demographic, laboratory, and outcome data were collected in conjunction with computed tomography scans performed within 3 months of listing.

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