Twitter As a Noninvasive Bio‐Marker for Trends in Liver Disease

Ben L. Da, Pallavi Surana, Samuel A. Schueler, Niloofar Y. Jalaly, Natasha Kamal, Sonia Taneja, Anusha Vittal, Christy L. Gilman, Theo Heller, Christopher Koh – 13 July 2019 – With the success of hepatitis C virus (HCV) direct‐acting antiviral therapies, there has been a shift in research focus to the other major chronic liver diseases (CLDs). The use of social media, specifically Twitter, has become a popular platform for understanding public health trends and for performing health care research.

Diagnosis, Outcome, and Management of Chylous Ascites Following Pediatric Liver Transplantation

Mar Miserachs, Eberhard Lurz, Aviva Levman, Anand Ghanekar, Mark Cattral, Vicky Ng, David Grant, Yaron Avitzur – 13 July 2019 – Data on postoperative chylous ascites (CA) after pediatric liver transplantation (LT) are scarce. This retrospective study was conducted to identify the incidence, risk factors, management, and outcomes of postoperative CA in a large single‐center pediatric LT cohort (2000‐2016). The study cohort comprised 317 LTs (153 living donors and 164 deceased donors) in 310 recipients with a median age of 2.7 years.

Nutritional Assessment in Inpatients With Cirrhosis Can Be Improved After Training and Is Associated With Lower Readmissions

Bradley Reuter, Jawaid Shaw, Jennifer Hanson, Victoria Tate, Chathur Acharya, Jasmohan S. Bajaj – 13 July 2019 – Malnutrition is widely prevalent in cirrhosis patients, which can worsen sarcopenia, hepatic encephalopathy (HE), and overall prognosis. We aimed to define the frequency of nutritional assessments of patients with cirrhosis in retrospective and prospective (after educational training) cohorts and to evaluate prospective changes along with their effects on 90‐day readmissions. This study was conducted in 2 phases.

Older Donor Age Is a Risk Factor for Negative Outcomes After Adult Living Donor Liver Transplantation Using Small‐for‐Size Grafts

Mahmoud Macshut, Toshimi Kaido, Siyuan Yao, Shintaro Yagi, Takashi Ito, Naoko Kamo, Kazuyuki Nagai, Mohamed Sharshar, Shinji Uemoto – 12 July 2019 – Adult‐to‐adult living donor liver transplantation (ALDLT) using small‐for‐size grafts (SFSGs), ie, a graft with a graft‐to‐recipient weight ratio (GRWR) <0.8%, has been a challenge that should be carefully dealt with, and risk factors in this category are unclear. Therefore, we aimed to examine the risk factors and outcomes of ALDLT using SFSGs over a 13‐year period in 121 patients who had undergone their first ALDLT using SFSGs.

Characterization of Gut Microbiota, Bile Acid Metabolism, and Cytokines in Intrahepatic Cholangiocarcinoma

Xiaodong Jia, Shanshan Lu, Zhen Zeng, Qingyan Liu, Zheng Dong, Yan Chen, Zhenyu Zhu, Zhixian Hong, Ting Zhang, Guifang Du, Jiao Xiang, Dawei Wu, Wenlin Bai, Bin Yang, Yinyin Li, Jiagan Huang, Haiyang Li, Rifaat Safadi, Yinying Lu – 12 July 2019 – Intrahepatic cholangiocarcinoma (ICC), a type of bile duct cancer, has a high mortality rate. Gut microbiota, bile acid (BA) metabolism, and cytokines have not been characterized in patients with ICC, and better noninvasive diagnostic approaches for ICC are essential to be established.

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