Kyle E. Korolowizc, Bin Li, Xu Huang, Changsuek Yon, Evelyn Rodrigo, Manny Corpuz, David M. Plouffe, Bhaskar V. Kallakury, Manasa Suresh, Tom Y.‐H. Wu, Andrew T. Miller, Stephan Menne – 8 July 2019 – Current therapeutics for chronic infection with hepatitis B virus (HBV) rarely induce functional cure due to the immunotolerant status of patients. Small molecule agonists targeting toll‐like receptor 7 (TLR7) have been shown to elicit a functional cure in animal models of HBV but sometimes with poor tolerability due to immune‐related toxicities.

Rianne A. Weersink, Joost P.H. Drenth, Nicole G.M. Hunfeld, Sander D. Borgsteede – 8 July 2019

Yongzhen Liu, Hui Liu, Zhanying Hu, Yang Ding, Xiao‐Ben Pan, Jun Zou, Jingyuan Xi, Guangxin Yu, Hongxin Huang, Meng‐Ting Luo, Fang Guo, Shuang Liu, Qiuju Sheng, Jidong Jia, Yong‐Tang Zheng, Jie Wang, Xiangmei Chen, Ju‐Tao Guo, Lai Wei, Fengmin Lu – 6 July 2019 – Nucleos(t)ide analogues (NAs) have been widely used for the treatment of chronic hepatitis B (CHB). Because viral DNA polymerase lacks proofreading function (3′ exonuclease activity), theoretically, the incorporated NAs would irreversibly terminate viral DNA synthesis.

Alexandre Louvet, Aleksander Krag – 6 July 2019

Lindsey Kennedy, Heather Francis, Gianfranco Alpini – 5 July 2019

Young‐Dong Yu, Regina Hwang, Karim J. Halazun, Adam Griesemer, Tomoaki Kato, Jean Emond, Benjamin Samstein – 5 July 2019

Tiffany C. Lee, Tiffany E. Kaiser, Keith Luckett, Koffi Wima, Leah K. Winer, Mackenzie C. Morris, Al‐Faraaz Kassam, Kamran Safdar, Khurram Bari, Nadeem Anwar, R. Cutler Quillin, Shimul A. Shah – 5 July 2019

Lars Cornelis Pietersen, Elise Sarton, Ian Alwayn, Hwai‐Ding Lam, Hein Putter, Bart Hoek, Andries Erik Braat – 5 July 2019 – The use of a temporary portocaval shunt (TPCS) as well as the order of reperfusion (initial arterial reperfusion [IAR] versus initial portal reperfusion) in orthotopic liver transplantation (OLT) is controversial and, therefore, still under debate.

Lauren Nephew, Zahra Zia, Marwan Ghabril, Eric Orman, Craig Lammert, Naga Chalasani – 4 July 2019 – Racial and ethnic differences in the presentation and outcomes of patients wait‐listed with acute liver failure (ALF) have not been explored. Adult patients with ALF wait‐listed for liver transplantation (LT) from 2002 to 2016 were investigated using the United Network for Organ Sharing database. Clinical characteristics and causative etiologies were compared between white, black, Hispanic, and Asian patients with ALF who were wait‐listed as status 1.

Quentin M. Anstee, Eric J. Lawitz, Naim Alkhouri, Vincent Wai‐Sun Wong, Manuel Romero‐Gomez, Takeshi Okanoue, Michael Trauner, Kathryn Kersey, Georgia Li, Ling Han, Catherine Jia, Lulu Wang, Guang Chen, G. Mani Subramanian, Robert P. Myers, C. Stephen Djedjos, Anita Kohli, Natalie Bzowej, Ziad Younes, Shiv Sarin, Mitchell L. Shiffman, Stephen A. Harrison, Nezam H. Afdhal, Zachary Goodman, Zobair M. Younossi – 4 July 2019 – Accurate noninvasive tests (NITs) are needed to replace liver biopsy for identifying advanced fibrosis caused by nonalcoholic steatohepatitis (NASH).